Docetaxel Impurity 60 CAS CATO-C4X-161960
| CAS No. | CATO-C4X-161960 |
| Molecular Formula | C76H83Cl3N2O22 |
| Molecular Weight | 1482.83 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C76H83Cl3N2O22, Docetaxel Impurity 60 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 1482.83 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Docetaxel Impurity 60 (CAS CATO-C4X-161960, C76H83Cl3N2O22) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C76H83Cl3N2O22 |
| Molecular Weight | 1482.83 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 35.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Docetaxel Standards
- Docetaxel Impurity 58 (CAS CATO-C4X-161958)
- Docetaxel Impurity 39 (CAS 859498-31-0)
- Docetaxel Impurity 87 (CAS CATO-C4X-161987)
- Docetaxel Impurity 11 (CAS 114915-14-9)
- Docetaxel Impurity 21 (CAS 151636-78-1)
- Docetaxel Impurity 74 (CAS CATO-C4X-161974)
- Docetaxel Impurity 75 (CAS CATO-C4X-161975)
- Docetaxel Impurity 56 (CAS CATO-C4X-161956)
Recommended Standards
- Bactenecin (CAS 116229-36-8)
- AP 20187 (CAS 195514-80-8)
- 2,2,4,4,6,6-Hexakis(hexadecyl)-1,3,5,2,4,6-trioxatrisilinane (CAS 139231-91-7)
- Anidulafungin Impurity 1 (CAS 3011727-42-4)
- Atracurium impurity 101 (CAS CATO-C4X-1850101)
- Cefazolin Impurity 30 (CAS CATO-C4X-157730)
- Folic Acid Impurity 45 (CAS 1182291-60-6)
- 4-Chloro-5-iodo-3-nitropyridin-2(1H)-one (CAS 2273883-66-0)
- (Des-Gly)-Glutathione-monoethyl ester (reduced) (CAS 114627-30-4)
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- (2S,3R,4R,5R)-5-(benzyloxymethyl)-3-[tert-butyl(diphenyl)silyl]oxy-tetrahydrofuran-2,4-diol (CAS 1583259-72-6)
- CL2 Linker (CAS 2270986-66-6)
- (S)-2-morpholino-1-phenylethan-1-amine dihydrochloride (CAS 915009-79-9)
- Des-Trp25-Tirzepatide (CAS CATO-CPTD788948)
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