Dolutegravir Impurity 63 CAS CATO-C4X-162063
| CAS No. | CATO-C4X-162063 |
| Molecular Formula | C14H14N2O7 |
| Molecular Weight | 322.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Dolutegravir Impurity 63 (C14H14N2O7) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Dolutegravir Impurity 63 (CAS CATO-C4X-162063) is a certified pharmaceutical impurity reference standard with the molecular formula C14H14N2O7 and a molecular weight of 322.27 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Dolutegravir Impurity 63 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H14N2O7 |
| Molecular Weight | 322.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Dolutegravir Standards
- Dolutegravir Impurity 57 (CAS 2958649-37-9)
- Dolutegravir Impurity 13 (CAS 1646862-02-3)
- Dolutegravir Impurity 56 (CAS CATO-C4X-162056)
- Dolutegravir Impurity N1 (CAS 1335210-34-8)
- Dolutegravir Impurity 24 (CAS 2315439-81-5)
- Dolutegravir Impurity 25 (CAS 2730133-58-9)
- Dolutegravir Impurity 3 (CAS CATO-C4X-16203)
- Dolutegravir Impurity 41 (CAS CATO-C4X-162041)
Recommended Standards
- Fluconazole Impurity 52 (CAS CATO-C4X-101952)
- N-(4-(2-Amino-2-oxoethyl)phenyl)-2-(trifluoromethyl)benzamide (CAS 1060283-08-0)
- Fluconazole N-Oxide (CAS 1997296-62-4)
- 2-(Methylthio)-8-nitro-6-(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one (CAS 1344087-73-5)
- Mexiletine Impurity 15 (CAS CATO-C4X-192915)
- Carprofen EP Impurity H (CAS 92841-23-1)
- Levosimendan impurity 77 (CAS CATO-C4X-130877)
- 4-(Cyclopentylmethyl)tetrahydro-2h-pyran-4-carboxylic acid (CAS 1342667-52-0)
- 1,3-Diethyl 2-(3-methylbut-2-en-1-yl)propanedioate (CAS 22539-80-6)
- 1-(4-Methoxy-3-methylphenyl)propan-1-amine (CAS 105321-37-7)
- 2-Chloro-3-(2-chloro-4-(trifluoromethyl)phenyl)propanoic acid (CAS 680215-64-9)
- 6-(4-Bromophenyl)-3-(pyrrolidin-2-yl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1706443-52-8)
- 1-Benzyl-5-methyl-1h-pyrazol-4-amine (CAS 1248908-53-3)
- (D-Ala1)-Peptide T amide (CAS 106362-34-9)
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