Fluconazole Impurity 52 CAS CATO-C4X-101952
| CAS No. | CATO-C4X-101952 |
| Molecular Formula | C13H12F2N6O2 |
| Molecular Weight | 322.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Fluconazole Impurity 52 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Fluconazole Impurity 52 (CAS CATO-C4X-101952), a pharmacopoeial impurity reference standard (molecular formula C13H12F2N6O2, MW 322.27 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Fluconazole Impurity 52 (C13H12F2N6O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H12F2N6O2 |
| Molecular Weight | 322.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Fluconazole Standards
- Fluconazole N-Oxide (CAS 1997296-62-4)
- Fluconazole EP Impurity I (CAS 749821-19-0)
- Fluconazole EP Impurity I (R-Isomer) (CAS CATO-C4X-101967)
- Fluconazole Impurity 48 (CAS 1222655-38-0)
- Fluconazole Impurity 61 (CAS CATO-C4X-101961)
- Fluconazole Impurity 72 (CAS CATO-C4X-101972)
- Fluconazole Impurity 73 (CAS CATO-C4X-101973)
- Fluconazole EP Impurity H (CAS 150194-52-8)
Recommended Standards
- Dolutegravir Impurity 63 (CAS CATO-C4X-162063)
- 781650-41-7 (3R,6S)-3-Amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one DTXSID50635341 (CAS 781650-41-7)
- N-(4-(2-Amino-2-oxoethyl)phenyl)-2-(trifluoromethyl)benzamide (CAS 1060283-08-0)
- N-(3-Dibenzofuranyl)-5-nitro-2-furancarboxamide (CAS 329198-87-0)
- Diosmin EP Impurity F (CAS 520-34-3)
- Levofloxacin Impurity 84 (CAS CATO-C4X-137184)
- Cholecalciferol impurity 22 (CAS CATO-C4X-158622)
- TEtrakis(Trifluoroacethoxy)Silane (CAS 2377-86-8)
- (S)-(+)-Ibuprofen Acid Chloride (CAS 115588-20-0)
- 4-Methoxyphenyl mesylate (CAS 19013-30-0)
- rel-(S)-5-(Hydroxymethyl)-3-((R)-1-phenylethyl)oxazolidin-2-one (CAS 480424-72-4)
- N-(4-(hydrazinecarbonyl)phenyl)acetamide (CAS 41764-73-2)
- 5-(P-tolyl)-1-(3-(trifluoromethyl)phenyl)-1H-imidazole-2-thiol (CAS 1105189-12-5)
- Atrial Natriuretic Polypeptide (4-28), human (CAS 95896-08-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com