Estradiol Impurity 53 CAS CATO-C4X-163653
| CAS No. | CATO-C4X-163653 |
| Molecular Formula | C30H32O |
| Molecular Weight | 408.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Estradiol Impurity 53 (CAS CATO-C4X-163653, C30H32O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Estradiol Impurity 53 (C30H32O) contains a steroid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 408.57 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Estradiol Impurity 53 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C30H32O |
| Molecular Weight | 408.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Estradiol Standards
- Estradiol Impurity 32 (CAS CATO-C4X-163632)
- Estradiol Impurity 46 (CAS CATO-C4X-163646)
- Estradiol-3,17b-dibutyrate (CAS 63042-23-9)
- Estradiol Benzoate EP Impurity H (CAS 4954-17-0)
- Estradiol Impurity 18 (CAS 63042-22-8)
- β-Estradiol 17-Cypionate (CAS 313-06-4)
- Estradiol Impurity 47 (CAS CATO-C4X-163647)
- Estradiol Valerate Impurity 11 (CAS CATO-C4X-284211)
Recommended Standards
- Oseltamivir impurity 235 (CAS CATO-C4X-1720235)
- Ursodeoxycholic Acid EP Impurity D (CAS 2955-27-3)
- Oseltamivir impurity 273 (CAS CATO-C4X-1720273)
- 3β-Cholic Acid (CAS 3338-16-7)
- Nefopam Impurity 30 (CAS CATO-C4X-283730)
- Cilastatin Impurity 34 (CAS CATO-C4X-196034)
- Cefoxitin Impurity 46 (CAS CATO-C4X-157846)
- (S)-Benzyl 2-(hydroxymethyl)piperazine-1-carboxylate (CAS 1217675-92-7)
- (2-(tert-Butoxy)-6-cyclopropoxyphenyl)methanamine (CAS 1243386-02-8)
- ζ-Stat trisodium (CAS 31894-34-5)
- 3-(4-Fluoro-3,5-dimethylphenyl)propanoic acid (CAS 1017779-63-3)
- Sivelestat Impurity 15 (CAS 526-21-6)
- 2-bromododecane (CAS 13187-99-0)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
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