Sildenafil EP Impurity F-d8 (N-Desmethyl Sildenafil-d8) CAS 1185168-06-2
| CAS No. | 1185168-06-2 |
| Molecular Formula | - |
| Molecular Weight | 468.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 468.60 g/mol gives Sildenafil EP Impurity F-d8 (N-Desmethyl Sildenafil-d8) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Sildenafil EP Impurity F-d8 (N-Desmethyl Sildenafil-d8) (CAS 1185168-06-2) is a certified pharmaceutical impurity reference standard with the molecular formula C21H20D8N6O4S and a molecular weight of 468.60 g/mol.
Sildenafil EP Impurity F-d8 (N-Desmethyl Sildenafil-d8) (C21H20D8N6O4S) contains deuterium isotope labeling, a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Sildenafil EP Impurity F-d8 (N-Desmethyl Sildenafil-d8) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H20D8N6O4S |
| Molecular Weight | 468.60 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Sildenafil Standards
- Sildenafil Impurity 75 (CAS 804518-64-7)
- Sildenafil Impurity 290 (CAS CATO-C4X-1128290)
- Sildenafil Impurity 293 (CAS CATO-C4X-1128293)
- Sildenafil Impurity 97 (CAS CATO-C4X-112897)
- Sildenafil (CAS 139755-83-2)
- Iso Sildenafil (CAS 253178-46-0)
- Sildenafil Impurity 10 (CAS 1393816-99-3)
- Sildenafil Impurity 283 (CAS CATO-C4X-1128283)
Recommended Standards
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- Exemestane Impurity 38 (CAS CATO-C4X-164138)
- Lasmiditan Impurity 4 (CAS 103640-16-0)
- Oxacillin Impurity 50 (CAS CATO-C4X-232150)
- Paroxetine Impurity 44 (CAS 317323-77-6)
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- N-(4-aminophenyl)-2-(azepan-1-yl)acetamide (CAS 937633-52-8)
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- 4-Methylisoxazolidin-3-one (CAS 62242-99-3)
- 2-(4-Bromophenyl)benzoxazole (CAS 3164-13-4)
- 4-Cyclopropoxy-N,N,5-trimethylpicolinamide (CAS 1243403-46-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com