Fluorouracil Impurity 18 CAS CATO-C4X-164918
| CAS No. | CATO-C4X-164918 |
| Molecular Formula | C4H7FN2O4 |
| Molecular Weight | 166.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Fluorouracil Impurity 18 (C4H7FN2O4) contains a carbohydrate-derived structure, an amide group, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Fluorouracil Impurity 18 (CAS CATO-C4X-164918) is a certified pharmaceutical impurity reference standard with the molecular formula C4H7FN2O4 and a molecular weight of 166.11 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H7FN2O4 |
| Molecular Weight | 166.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorouracil Standards
- Fluorouracil Impurity 17 (CAS 5440-00-6)
- Fluorouracil Impurity 27 (CAS 2566704-13-8)
- Fluorouracil Impurity 23 (CAS CATO-C4X-164923)
- Fluorouracil Impurity 29 (CAS CATO-C4X-164929)
- Fluorouracil Impurity 8 (CAS 726207-85-8)
- Fluorouracil EP Impurity F (CAS 56177-80-1)
- Fluorouracil Impurity 28 (CAS CATO-C4X-164928)
- Fluorouracil Impurity 11 (Mixture of Diastereomers) (CAS 37103-91-6)
Recommended Standards
- Fosfomycin Impurity 81 (CAS 734473-80-4)
- Biphenyl-<SUP>13</SUP>C<SUB>12</SUB> (CAS 104130-36-1)
- Fosfomycin Impurity 62 (CAS CATO-C4X-131662)
- 2,2-difluoro-2-(furan-2-yl)acetic acid (CAS 1344257-62-0)
- Sacubitril Impurity 40 (CAS CATO-C4X-280940)
- N-Niroso Bilastine Impurity 77 (CAS CATO-C4X-225377)
- Ibrutinib Impurity 119 (CAS CATO-C4X-1064119)
- 1219184-45-8 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)heptanoic acid (CAS 1219184-45-8)
- 1,2,4,6,7,9-Hexachlorodibenzo[b,d]furan (CAS 75627-02-0)
- N-(Piperidin-4-yl)-2-(thiophen-2-yl)acetamide (CAS 1018619-37-8)
- 2-bromo-6-chloro-3-fluorobenzoic acid (CAS 1781926-06-4)
- 4-(3-Nitrophenyl)-2-phenylbenzofuran (CAS 863871-00-5)
- 5-(4-Hydroxyphenyl)pyrrolidin-2-one (CAS 207989-87-5)
- Semaglutide impurity 194 (CAS CATO-C4X-2226194)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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