Lidocaine Impurity 98 CAS CATO-C4X-167998
| CAS No. | CATO-C4X-167998 |
| Molecular Formula | C16H27N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lidocaine Impurity 98.
Lidocaine Impurity 98 (CAS CATO-C4X-167998) is a certified pharmaceutical impurity reference standard with the molecular formula C16H27N2O2Br and a molecular weight of 359.31 g/mol.
Lidocaine Impurity 98 (C16H27N2O2Br) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Lidocaine Impurity 98 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H27N2O2 Br |
| Molecular Weight | 359.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Lidocaine Standards
- Lidocaine EP Impurity J HCl (CAS 1012864-23-1)
- Lidocaine Impurity 70 HCl (CAS 101651-71-2)
- Lidocaine Impurity 57 (CAS 102878-74-0)
- Lidocaine Impurity 19 (CAS 108-69-0)
- Lidocaine EP Impurity H (CAS 1131-01-7)
- Lidocaine EP Impurity E Hydrochloride (CAS 1135231-62-7)
- Lidocaine-d10 Hydrochloride (CAS 1189959-13-4)
- Lidocaine EP Impurity D-d6 (CAS 1216698-89-3)
Recommended Standards
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- tert-butyl N-[(1S,3S)-3-(hydroxymethyl)cyclopentyl]carbamate (CAS 497159-95-2)
- 4-Methylbenzo[d]oxazole-2-carbonitrile (CAS 1806393-72-5)
- 4-(3,5-Dimethylbenzoyl)quinoline (CAS 1706456-87-2)
- Posaconazole Impurity 89 (CAS CATO-C4X-1208189)
- [5-(Pyrrolidin-1-ylsulfonyl)-2-furyl]methylamine hydrochloride (CAS 1241675-86-4)
- 5-Chloro-2-cyclopropyl-6-(methyl(2-phenylcyclopropyl)amino)pyrimidine-4-carboxylic acid (CAS 1956369-25-7)
- [3-31]-Semaglutide D (Sodium salt) (CAS CATO-C4X-2226119)
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