LCZ-696 Impurity 11 CAS CATO-C4X-169611
| CAS No. | CATO-C4X-169611 |
| Molecular Formula | C25H31NO5 |
| Molecular Weight | 425.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of LCZ-696 Impurity 11 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, LCZ-696 Impurity 11 (CAS CATO-C4X-169611, C25H31NO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
LCZ-696 Impurity 11 (C25H31NO5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), LCZ-696 Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H31NO5 |
| Molecular Weight | 425.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Recommended Standards
- Valsartan Impurity 146 (CAS CATO-C4X-1057146)
- Sacubitril Impurity 20 (CAS 2459446-51-4)
- tert-butyl N-(tert-butoxycarbonylamino)-N-[3-(4-nitrophenyl)-1-bicyclo[1.1.1]pentanyl]carbamate (CAS 2149634-57-9)
- Sacubitril Impurity 37 (CAS CATO-C4X-280937)
- Upadacitinib Impurity 146 (CAS CATO-C4X-2405146)
- Edaravone Impurity 34 (CAS 2762440-11-7)
- Lurasidone Impurity N67 (CAS 194861-74-0)
- (E)-N'-[(3-Chloro-2-fluorophenyl)methoxy]-N-{thieno[2,3-d]pyrimidin-4-yl}methanimidamide (CAS 477846-35-8)
- 2H-Pyrido[4,3-b]indol-2-ol (CAS 66570-76-1)
- 1-Amino-2-methyl-4-oxo-4,5-dihydro-1H-pyrrole-3-carboxylic acid (CAS 156495-76-0)
- 4-Cyano-N-(5-methylthiazol-2-yl)benzamide (CAS 797016-38-7)
- Chlorpheniramine Impurity 12 (CAS 20619-13-0)
- Sorbitan sesquistearate (CAS 51938-44-4)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
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