LCZ-696 Impurity 76 CAS CATO-C4X-169676
| CAS No. | CATO-C4X-169676 |
| Molecular Formula | - |
| Molecular Weight | 415.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 415.52 g/mol gives LCZ-696 Impurity 76 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies LCZ-696 Impurity 76 (CAS CATO-C4X-169676), a pharmacopoeial impurity reference standard (molecular formula C24H25D4NO5, MW 415.52 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of LCZ-696 Impurity 76 (C24H25D4NO5) is characterized by deuterium isotope labeling, a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures LCZ-696 Impurity 76 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H25D4NO5 |
| Molecular Weight | 415.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Recommended Standards
- Sacubitril-d4 (CAS 1884269-07-1)
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- Drotaverine Impurity 2 (CAS 6298-46-0)
- Olaparib Impurity 54 (CAS 63964-50-1)
- Lidocaine Impurity 39 (CAS 77966-82-6)
- Mirogabalin Impurity N78 (CAS CATO-CP155178)
- 4-Chloro-2-(pyridin-2-yl)pyrimidine (CAS 97603-38-8)
- 1-(2-(6-(Phenylamino)pyridin-3-yl)pyrrolidin-1-yl)ethanone (CAS 1352501-21-3)
- 4-(Tert-butyl)-N-(1,5,6-trimethyl-1H-benzo[d]imidazol-4-yl)benzenesulfonamide (CAS 338411-11-3)
- Bromocriptine Impurity 16 (CAS CATO-C4X-136116)
- [3-(Cyclopropyl-methyl-amino)-pyrrolidin-1-yl]-acetic acid (CAS 1353954-42-3)
- 2-(Difluoromethyl)pyridin-3-amine (CAS 1805301-57-8)
- Neuroendocrine Regulatory Peptide-1 (rat) (CAS 954420-51-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com