Minocycline Impurity 67 CAS CATO-C4X-169967
| CAS No. | CATO-C4X-169967 |
| Molecular Formula | C21H21IN2O7 |
| Molecular Weight | 540.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Minocycline Impurity 67 (CAS CATO-C4X-169967) is a certified pharmaceutical impurity reference standard with the molecular formula C21H21IN2O7 and a molecular weight of 540.31 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution, Minocycline Impurity 67 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 540.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H21IN2O7 |
| Molecular Weight | 540.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related Minocycline Standards
- Minocycline Impurity 71 (CAS CATO-C4X-169971)
- Minocycline Impurity 64 (CAS CATO-C4X-169964)
- Minocycline impurity 73 (CAS 156263-28-4)
- Minocycline Impurity 43 (CAS 28698-94-4)
- Minocycline Impurity 26 (CAS 149934-16-7)
- Minocycline EP Impurity G (CAS 601455-95-2)
- Minocycline Dehydro Impurity (CAS CATO-C4X-16995)
- Minocycline Impurity 54 (CAS CATO-C4X-169954)
Recommended Standards
- Bromhexine Impurity 19 (CAS CATO-C4X-106019)
- 4,7-Bis(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzo[c][1,2,5]thiadiazole (CAS 1436849-96-5)
- Sarecycline Impurity 3 (CAS CATO-C4X-27983)
- 2',3'-Bis(4-bromophenyl)-1,1':4',1''-terphenyl (CAS 1397262-58-6)
- Sacubitril Impurity 22 (CAS 2459446-53-6)
- Azilsartan Methyl Ester Impurity (CAS 147403-52-9)
- Sulfadiazine Impurity 18 (CAS 345936-70-1)
- Methyl 2-acetyl-2H-indazole-4-carboxylate (CAS 1303890-10-9)
- 4-(2-Aminoethyl)-5-oxo-3-phenyl-2,5-dihydro-1H-pyrazole-1-carboxamide sulfate (CAS 1177324-62-7)
- 1-[4-(Methylsulfonyl)-2-nitrophenyl]piperidine-2-carboxylic acid (CAS 1214141-18-0)
- 1-Cyclohexyl-1H-benzo[d]imidazol-5-amine (CAS 385381-36-2)
- 4-Methyl-N-[(E)-2-(1-nitronaphthalen-2-yl)ethenyl]aniline (CAS 339015-86-0)
- (R)-tert-Butyl 3-(2-oxoethyl)piperidine-1-carboxylate (CAS 1039361-81-3)
- D-[Thr]5-Semaglutide (CAS CATO-C4X-2226245)
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