N-Nitroso Minocycline impurity 77 CAS CATO-C4X-169977
| CAS No. | CATO-C4X-169977 |
| Molecular Formula | C20H20ClN3O9 |
| Molecular Weight | 481.84 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
N-Nitroso Minocycline impurity 77 (CAS CATO-C4X-169977) is a certified pharmaceutical impurity reference standard with the molecular formula C20H20ClN3O9 and a molecular weight of 481.84 g/mol.
Based on its molecular formula C20H20ClN3O9, N-Nitroso Minocycline impurity 77 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 481.84 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H20ClN3O9 |
| Molecular Weight | 481.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- N-Nitroso Cloxacillin Impurity 33 (CAS CATO-C4X-159733)
- N-nitroso-desmethyl-demeclocycline (CAS CATO-C4X-160811)
- N-Nitroso Dequalinium impurity 36 (CAS CATO-C4X-193636)
- N-Nitroso Aripiprazole (CAS CATO-C4X-100868)
- N-Nitroso Dalpiciclib impurity 2 (CAS CATO-C4X-32952)
- N2-Nitroso Levomefolic Acid (CAS CATO-C4X-139549)
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- N-Nitroso Sildenafil EP Impurity F (CAS CATO-C4X-112883)
Recommended Standards
- Dodecyl octadecylcarbamate (CAS 84967-21-5)
- 3,3',5,5'-Tetrabromo-2,2'-bithiophene (CAS 125143-53-5)
- 2-((4-Chlorobenzyl)thio)-4,6-bis(4-chlorophenyl)nicotinonitrile (CAS 332385-86-1)
- Ethyl 2-{N'-[(1E)-(4-chlorophenyl)methylidene]hydrazinecarbonyl}-3-{[3-(trifluoromethyl)phenyl]carbamoyl}cyclopropane-1-carboxylate (CAS 321385-55-1)
- Edaravone impurity 41 (CAS CATO-C4X-106241)
- Estradiol Benzoate EP Impurity G (CAS 2393-53-5)
- Voglibose Impurity 25 (CAS CATO-C4X-178025)
- 2-chloro-6-hydroxy-4-methylbenzaldehyde (CAS 1427396-37-9)
- (E)-1,3-dimethoxy-5-(2-nitrovinyl)benzene (CAS 86255-43-8)
- 1265AH 17(S)-HETE 183509-25-3 C20H32O3 (CAS 183509-25-3)
- Omadacycline impurity 20 (CAS CATO-C4X-285720)
- Gadoteridol impurity 30 (CAS 2172857-50-8)
- (4-Fluorophenyl)(3-methyl-1-benzofuran-2-yl)methanone (CAS 303145-26-8)
- Insulin Detemir (CAS 169148-63-4)
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