Pemetrexed Impurity 68 CAS CATO-C4X-172668
| CAS No. | CATO-C4X-172668 |
| Molecular Formula | C20H21N5O6 |
| Molecular Weight | 427.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Pemetrexed Impurity 68 (CAS CATO-C4X-172668) is a certified pharmaceutical impurity reference standard with the molecular formula C20H21N5O6 and a molecular weight of 427.41 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Pemetrexed Impurity 68 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 427.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Pemetrexed Impurity 68 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H21N5O6 |
| Molecular Weight | 427.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Pemetrexed Standards
- (+/-)-Pemetrexed (CAS 756887-58-8)
- Pemetrexed Impurity 13 (CAS CATO-C4X-172613)
- Pemetrexed (CAS 137281-23-3)
- Pemetrexed EP Impurity E (CAS 182009-04-7)
- Pemetrexed Impurity 27 (CAS CATO-C4X-172627)
- Pemetrexed Impurity 9 (CAS 193281-05-9)
- Pemetrexed Impurity 65 (CAS CATO-C4X-172665)
- Pemetrexed Impurity (CAS 1644286-35-0)
Recommended Standards
- Cariprazine (CAS 839712-12-8)
- Cariprazine Impurity 4 (CAS CATO-C4X-24084)
- Cariprazine Impurity 45 (CAS 1378235-50-7)
- Pomalidomide-CO-PEG2-propargyl (CAS 2243000-25-9)
- Arotinolol Impurity 23 (CAS CATO-C4X-185423)
- Chlorhexidine EP Impurity J (CAS CATO-C4X-225614)
- Pimavanserin Impurity 28 (CAS CATO-C4X-193828)
- Benzyl-D-aspartic acid (CAS 6367-42-6)
- 1-(Tert-butoxycarbonyl)-3-phenylpiperidine-3-carboxylic acid (CAS 1203685-64-6)
- Avanafil Impurity 144 (CAS CATO-C4X-1118144)
- (R)-3-Aminohexan-1-ol hydrochloride (CAS 68889-63-4)
- 5-Ethyl-5,6,7,8-tetrahydropyrido[3,4-b]pyrazine (CAS 785777-01-7)
- 7-(Piperazin-1-yl)benzo[d]oxazol-2(3H)-one hydrochloride (CAS 848154-38-1)
- Insulin Degludec Impurity 3 (CAS CATO-C4X-21573)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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