Cariprazine Impurity 45 CAS 1378235-50-7
| CAS No. | 1378235-50-7 |
| Molecular Formula | C21H32Cl2N4O |
| Molecular Weight | 427.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Cariprazine Impurity 45 (CAS 1378235-50-7) is a certified pharmaceutical impurity reference standard with the molecular formula C21H32Cl2N4O and a molecular weight of 427.41 g/mol.
Cariprazine Impurity 45 (C21H32Cl2N4O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Cariprazine Impurity 45 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H32Cl2N4O |
| Molecular Weight | 427.41 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Cariprazine Standards
- Cariprazine (CAS 839712-12-8)
- Cariprazine Impurity 4 (CAS CATO-C4X-24084)
- Cariprazine Impurity 9 (CAS 1480744-38-4)
- Cariprazine Impurity 63 (CAS CATO-C4X-240863)
- Cariprazine Impurity 41 (CAS 1957145-61-7)
- Cariprazine-d6 (CAS 1308278-67-2)
- Cariprazine Impurity 18 (CAS CATO-C4X-240818)
- Cariprazine Impurity 36 (CAS CATO-C4X-240836)
Recommended Standards
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- N-(2-Hydroxyethyl)-1-(4-(3,4,5-trifluorobenzyl)pyridin-2-yl)indoline-4-carboxamide (CAS 1956366-29-2)
- Pemetrexed EP Impurity E (CAS 182009-04-7)
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- 5-Chloro-4-fluoronicotinonitrile (CAS 1256834-80-6)
- 4,4-Dimethyldihydrothiophen-3(2H)-one 1,1-dioxide (CAS 5324-60-7)
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- 2-(4-(Dimethylamino)styryl)benzo[d]oxazol-6-ol (CAS 917763-27-0)
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