Pimecrolimus Impurity 5 CAS CATO-C4X-17315
| CAS No. | CATO-C4X-17315 |
| Molecular Formula | C44H70ClNO11 |
| Molecular Weight | 824.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Pimecrolimus Impurity 5 (CAS CATO-C4X-17315), a pharmacopoeial impurity reference standard (molecular formula C44H70ClNO11, MW 824.48 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Pimecrolimus Impurity 5 (C44H70ClNO11) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C44H70ClNO11 |
| Molecular Weight | 824.48 g/mol |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Pimecrolimus Standards
- Pimecrolimus Impurity 20 (CAS CATO-C4X-173120)
- Pimecrolimus Impurity 6 (CAS CATO-C4X-17316)
- Pimecrolimus (CAS 137071-32-0)
- Pimecrolimus Impurity 12 (CAS CATO-C4X-173112)
- Pimecrolimus Impurity 13 (CAS CATO-C4X-173113)
- Pimecrolimus Impurity 14 (CAS CATO-C4X-173114)
- Pimecrolimus Impurity 16 (CAS CATO-C4X-173116)
- Pimecrolimus Impurity 17 (CAS CATO-C4X-173117)
Recommended Standards
- Etoposide Impurity 37 (CAS CATO-C4X-202437)
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- IR-825 (CAS 1558079-49-4)
- C60 Derivative,indene-C60 monoadduct (CAS 172885-96-0)
- Efinaconazole Impurity 35 (CAS 127001-03-0)
- Penfluridol Impurity 13 (CAS CATO-C4X-353813)
- Levocarnitine Impurity 17 (CAS 90866-33-4)
- tert-Butyl trans-4-aminocyclohexylmethylcarbamate monHCl (CAS 192323-07-2)
- Zanamivir EP Impurity A (CAS CATO-C4X-205010)
- Ac-DL-Phg-OH (CAS 15962-46-6)
- (2-Amino-5-bromophenyl)(p-tolyl)methanone (CAS 5621-60-3)
- N-(2,3-dimethylphenyl)-3-(1H-pyrrol-1-yl)thiophene-2-carboxamide (CAS 866017-77-8)
- tert-Butyl (5-bromo-2-chloropyridin-3-yl)carbamate (CAS 193888-15-2)
- Tau Peptide (295-309) trifluoroacetate salt (CAS 330456-46-7)
Why CATO?
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