Etoposide Impurity 37 CAS CATO-C4X-202437

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-202437
Molecular FormulaC34H34Cl4O15
Molecular Weight824.44 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Etoposide Impurity 37 CAS CATO-C4X-202437 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 824.44 g/mol gives Etoposide Impurity 37 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

As a process- or degradation-related impurity, Etoposide Impurity 37 (CAS CATO-C4X-202437, C34H34Cl4O15) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Etoposide Impurity 37 (C34H34Cl4O15) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Etoposide Impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC34H34Cl4O15
Molecular Weight824.44 g/mol
Purity≥95%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)16.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl-containing

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