Prednisolone Sodium Phosphate USP Impurity I CAS CATO-C4X-173738
| CAS No. | CATO-C4X-173738 |
| Molecular Formula | C21H27O7P |
| Molecular Weight | 422.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Prednisolone Sodium Phosphate USP Impurity I (C21H27O7P) is characterized by a flavonoid core, a phosphate ester group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Prednisolone Sodium Phosphate USP Impurity I (CAS CATO-C4X-173738, C21H27O7P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Prednisolone Sodium Phosphate USP Impurity I meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H27O7P |
| Molecular Weight | 422.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Prednisolone Standards
- Prednisolone Impurity 16 (CAS CATO-C4X-173716)
- Prednisolone Impurity 69 (CAS 31311-61-2)
- Prednisolone Impurity 27 (CAS 76282-98-9)
- Prednisolone Impurity 49 (CAS CATO-C4X-173749)
- Prednisolone Impurity 61 (CAS 50718-16-6)
- Prednisolone Impurity 29 (CAS 106822-21-3)
- Prednisolone Impurity 40 (CAS CATO-C4X-173740)
- Prednisolone impurity 66 (CAS 137759-50-3)
Recommended Standards
- Ceftizoxime Impurity 47 (CAS CATO-C4X-179347)
- Flunarizine impurity 53 (CAS CATO-C4X-135753)
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- N-(4-(2-(1,3-dioxoisoindolin-2-yl)ethyl)thiazol-2-yl)-4-nitrobenzamide (CAS 866050-86-4)
- Posaconazole Impurity N2 (CAS 183871-36-5)
- Testosterone Impurity 30 (CAS CATO-C4X-243230)
- Cholic Acid Impurity 81 (CAS CATO-C4X-116081)
- tert-Butyl ((1-(6-ethoxypyrimidin-4-yl)piperidin-3-yl)methyl)carbamate (CAS 1353977-46-4)
- 4-[(3AR,4s,9bs)-6,8-dichloro-3a,4,5,9b-tetrahydro-3h-cyclopenta[c]quinolin-4-yl]benzoic acid (CAS 955964-05-3)
- N-(2,2-Dimethoxyethyl)-4-methoxy-1,3-benzodioxole-5-methanamine (CAS 108460-85-1)
- cyclopentanesulfonic acid (CAS 19247-73-5)
- n-Cyclopropyl-2-((4-fluorophenyl)thio)acetamide (CAS 1252378-57-6)
- ((2S,7aR)-2-Fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol-d1 (CAS 2883770-43-0)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
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