Flunarizine impurity 53 CAS CATO-C4X-135753
| CAS No. | CATO-C4X-135753 |
| Molecular Formula | C26H18F4O |
| Molecular Weight | 422.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 422.41 g/mol gives Flunarizine impurity 53 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Flunarizine impurity 53 (CAS CATO-C4X-135753), a pharmacopoeial impurity reference standard (molecular formula C26H18F4O, MW 422.41 g/mol) used for the identification and quantification of trace impurities in APIs.
Flunarizine impurity 53 (C26H18F4O) contains a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Flunarizine impurity 53 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H18F4O |
| Molecular Weight | 422.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Flunarizine Standards
- Flunarizine Impurity 7 (CAS 87166-81-2)
- Flunarizine Impurity N1 (CAS 123375-94-0)
- Flunarizine impurity 34 (CAS CATO-C4X-135734)
- Flunarizine Impurity 14 (CAS CATO-C4X-135714)
- Flunarizine Impurity 15 (CAS CATO-C4X-135715)
- Flunarizine impurity 39 (CAS 19422-37-8)
- Flunarizine EP Impurity C (CAS 90830-31-2)
- Flunarizine EP Impurity D（(Z)-Flunarizine） (CAS 693765-11-6)
Recommended Standards
- N-(4-(2-(1,3-dioxoisoindolin-2-yl)ethyl)thiazol-2-yl)-4-nitrobenzamide (CAS 866050-86-4)
- Prednisolone Impurity 16 (CAS CATO-C4X-173716)
- N'-(4-((4-Fluorobenzyl)oxy)benzylidene)-2-((3-nitrophenyl)amino)acetohydrazide (CAS 303090-90-6)
- Prednisolone Sodium Phosphate USP Impurity I (CAS CATO-C4X-173738)
- Opicapone Impurity 80 (CAS CATO-C4X-240480)
- Amisulpride EP Impurity E (CAS 71675-87-1)
- Argatroban Impurity 128 (CAS CATO-C4X-1007128)
- 1-(3-Hydroxyphenyl)propan-2-one (CAS 64479-84-1)
- tert-Butyl (S)-1-(3-(benzyloxy)-2-fluoropropyl)-1H-1,2,3-triazole-4-carboxylate (CAS 1853165-96-4)
- 4-CHLORO-6-METHYL-2-OXO-2H-CHROMENE-3-CARBALDEHYDE 51069-84-2 CTK4J3571 (CAS 51069-84-2)
- 2-Phenylisonicotinic Acid (CAS 55240-51-2)
- 2-Chloro-4-(chloromethyl)-6-(trifluoromethyl)pyridine (CAS 1196154-47-8)
- (3-((4-(Tert-butoxycarbonyl)piperazin-1-yl)sulfonyl)phenyl)boronic acid (CAS 914610-81-4)
- 3X Flag Peptide trifluoroacetate salt (CAS 402750-12-3)
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