Quinapril Hydrochloride EP Impurity H CAS CATO-C4X-17415
| CAS No. | CATO-C4X-17415 |
| Molecular Formula | C25H30N2O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Quinapril Hydrochloride EP Impurity H.
CATO supplies Quinapril Hydrochloride EP Impurity H (CAS CATO-C4X-17415), a pharmacopoeial impurity reference standard (molecular formula C25H30N2O5HCl, MW 474.98 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Quinapril Hydrochloride EP Impurity H is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 474.98 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Quinapril Hydrochloride EP Impurity H meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H30N2O5 HCl |
| Molecular Weight | 474.98 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Quinapril Standards
- Quinapril Bicyclic Acid Benzyl Ester (CAS 103733-30-8)
- Quinapril ethyl ester (CAS 103733-35-3)
- Quinapril ethyl ester maleic acid salt (CAS 103733-36-4)
- Quinapril EP Impurity D (CAS 103733-49-9)
- Quinapril EP Impurity I (CAS 103775-09-3)
- Quinapril EP Impurity G (CAS 103833-16-5)
- Quinapril EP Impurity C-d5 (CAS 1279034-23-9)
- Quinapril EP Impurity E (CAS 2055735-09-4)
Recommended Standards
- Raltitrexed Impurity 48 (CAS CATO-C4X-138648)
- Everolimus Impurity 47 (CAS CATO-C4X-112247)
- Benzylpenicillin Impurity 68 (CAS 30200-14-7)
- HDMI 1-(2-pyridyl piperazine) Derivative (CAS 337511-95-2)
- 6-bromopyrazolo[1,5-a]pyridine-3-carbonitrile (CAS 2092835-01-1)
- trans-3-Aminocyclobutaneacetic acid (CAS 1408076-11-8)
- (R)-cyclohexyl(phenyl)methanol (CAS 3113-96-0)
- Diethyl 2-(5-bromopyrimidin-2-yl)malonate (CAS 66621-92-9)
- 4-(Hydroxymethyl)bicyclo[2.1.1]Hexane-1-carbonitrile (CAS 2090415-26-0)
- HA Peptide (CAS 92000-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com