Quinapril EP Impurity I CAS 103775-09-3
| CAS No. | 103775-09-3 |
| Molecular Formula | C25H30N2O5 |
| Molecular Weight | 438.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Quinapril EP Impurity I (CAS 103775-09-3, C25H30N2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Quinapril EP Impurity I (C25H30N2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Quinapril EP Impurity I meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H30N2O5 |
| Molecular Weight | 438.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
Related Quinapril Standards
- Quinapril EP Impurity G (CAS 103833-16-5)
- Quinapril (CAS 85441-61-8)
- Quinapril EP Impurity E (CAS 2055735-09-4)
- Quinapril Isopropyl Ester Analog (CAS 955034-25-0)
- Quinapril impurity 3 (CAS CATO-C4X-17413)
- Quinapril EP Impurity D (CAS 103733-49-9)
- Quinapril EP Impurity C-d5 (CAS 1279034-23-9)
- Quinapril ethyl ester (CAS 103733-35-3)
Recommended Standards
- (S)-3,3'-Diphenyl-1,1'-binaphthalene-2,2'-diol (CAS 102490-05-1)
- Estetrol Impurity 10 (CAS 3088028-02-5)
- (2S,2'S)-N,N'-[(1R)-6,6'-dimethoxy[1,1'-biphenyl]-2,2'-diyl]bis-2-Pyrrolidinecarboxamide (CAS 1199642-39-1)
- Pimavanserin Impurity 11 (CAS CATO-C4X-193811)
- Cholesterol Impurity 17 (CAS 14214-69-8)
- Famotidine impurity 62 (CAS CATO-C4X-139262)
- Bimatoprost Impurity 14 (CAS CATO-C4X-196414)
- 3-(1-(4-Methylbenzyl)-3-phenyl-1h-pyrazol-4-yl)acrylic acid (CAS 1006494-72-9)
- [(Chloromethyl)sulfanyl]ethane (CAS 1708-73-2)
- Sodium cetyl/stearyl sulfate (CAS 68955-20-4)
- (S)-4-isopentyl-2-(pyrrolidin-2-yl)phenol (CAS 1213566-63-2)
- 7-Bromo-5-methyl-1H-indole-3-carbaldehyde (CAS 16077-60-4)
- Betamethasone 17-Propionate-d5 (CAS CATO-C4X-143735)
- Semaglutide impurity 206 (CAS CATO-C4X-2226206)
Why CATO?
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