Riociguat Impurity 11 CAS CATO-C4X-174911
| CAS No. | CATO-C4X-174911 |
| Molecular Formula | C21H20FN7O2 |
| Molecular Weight | 421.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Riociguat Impurity 11.
Riociguat Impurity 11 (CAS CATO-C4X-174911) is a certified pharmaceutical impurity reference standard with the molecular formula C21H20FN7O2 and a molecular weight of 421.43 g/mol.
Based on its molecular formula C21H20FN7O2, Riociguat Impurity 11 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 421.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Riociguat Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H20FN7O2 |
| Molecular Weight | 421.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 7 |
Related Riociguat Standards
- Riociguat Impurity 12 (CAS CATO-C4X-174912)
- Riociguat (CAS 625115-55-1)
- Riociguat Impurity 15 (CAS CATO-C4X-174915)
- Riociguat Impurity 22 (CAS CATO-C4X-174922)
- Riociguat Impurity 38 (CAS CATO-C4X-174938)
- Riociguat Impurity 21 (CAS CATO-C4X-174921)
- Riociguat-13C-d3 (CAS 1304478-43-0)
- Riociguat Impurity 17 (CAS CATO-C4X-174917)
Recommended Standards
- Adenosine Impurity 20 (CAS 42776-78-3)
- Adenosine 5’-Tosylate (CAS 5135-30-8)
- Cyclosulfamuron (CAS 136849-15-5)
- 4,6-Dimethyl-3-(4-methylbenzenesulfonyl)-2-[3-(trifluoromethyl)phenoxy]pyridine (CAS 478245-36-2)
- Calcitriol Impurity 35 (CAS CATO-C4X-151035)
- Rizatriptan Impurity 25 (CAS CATO-C4X-175225)
- Dronedarone Impurity 97 (CAS CATO-C4X-109297)
- Ethyl 5-(2-acetoxyphenyl)-5-oxopentanoate (CAS 898758-73-1)
- Clopidogrel thiol metabolite H3 (CAS 1352123-33-1)
- 3-Methyl-2-phenyl-2,3-dihydrobenzofuran (CAS 88329-95-7)
- 3-Acetylamino-5-fluoro-1H-indole-2-carboxylic acid (CAS 330439-67-3)
- Cedrusin Impurity 1 (3,4-O-Dimethylcedrusin) (CAS 166021-14-3)
- Ethyl 4-(1H-benzo[d][1,2,3]triazol-1-yl)butanoate (CAS 69218-48-0)
- Semaglutide impurity 275 (CAS CATO-C4X-2226275)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com