N-Nitroso Tiotropium impurity 52 CAS CATO-C4X-176452

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-176452
Molecular FormulaC18H20N2O5S2
Molecular Weight408.49 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

N-Nitroso Tiotropium impurity 52 CAS CATO-C4X-176452 chemical structure

Description

The molecular framework of N-Nitroso Tiotropium impurity 52 (C18H20N2O5S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

N-Nitroso Tiotropium impurity 52 (CAS CATO-C4X-176452) is a certified pharmaceutical impurity reference standard with the molecular formula C18H20N2O5S2 and a molecular weight of 408.49 g/mol.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures N-Nitroso Tiotropium impurity 52 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC18H20N2O5S2
Molecular Weight408.49 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms2
Sulfur Atoms2

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