Tolterodine EP Impurity E HCl CAS CATO-C4X-176711
| CAS No. | CATO-C4X-176711 |
| Molecular Formula | C19H25NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Tolterodine EP Impurity E HCl is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Tolterodine EP Impurity E HCl (CAS CATO-C4X-176711, C19H25NOHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Tolterodine EP Impurity E HCl (C19H25NOHCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H25NO HCl |
| Molecular Weight | 319.87 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Tolterodine Standards
- Tolterodine Impurity 21 (CAS 1043911-42-7)
- Tolterodine EP Impurity C (CAS 1161940-88-0)
- Tolterodine Impurity N5 (CAS 1189501-90-3)
- Rac- Tolterodine-D14 Hydrochloride (CAS 1246816-99-8)
- rac-Tolterodine-d14 Tartrate (CAS 1246911-91-0)
- Tolterodine Impurity 4 (CAS 124935-88-2)
- Tolterodine Impurity 18 (CAS 124935-89-3)
- rac-Tolterodine hydrochloride, 98% (CAS 124936-75-0)
Recommended Standards
- Tofacitinib Impurity 83 (CAS 1638499-33-8)
- Dotinurad Impurity 18 (CAS CATO-C4X-249418)
- Everolimus Impurity 45 (CAS CATO-C4X-112245)
- 2-Chloro-1-(naphthalen-2-yl)ethan-1-one (CAS 50846-93-0)
- 2-(2,4-Dichlorophenyl)-5-nitro-2H-1,2,3-triazole-4-carboxylic acid (CAS 1707609-43-5)
- tert-Butyl 2-(piperazin-1-yl)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate (CAS 1822810-14-9)
- 4,5-Dibromo-2-(4-chlorophenyl)pyridazin-3(2H)-one (CAS 14132-96-8)
- 2,3,4,5,6-Pentamethylphenylboronic Acid (CAS 1028205-76-6)
- Cilastatin Impurity 9 (CAS 131833-97-1)
- Peptide Fmoc-Thi-Thi-OH (CAS CATO-CPTD788552)
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