Vancomycin Impurity M CAS CATO-C4X-177522
| CAS No. | CATO-C4X-177522 |
| Molecular Formula | C66H75Cl2N9O24 |
| Molecular Weight | 1449.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Vancomycin Impurity M (CAS CATO-C4X-177522, C66H75Cl2N9O24) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Vancomycin Impurity M (C66H75Cl2N9O24) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C66H75Cl2N9O24 |
| Molecular Weight | 1449.25 g/mol |
| Purity | >80% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 33.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 9 |
Related Vancomycin Standards
- Vancomycin EP Impurity I (CAS CATO-C4X-177510)
- Vancomycin EP Impurity J (CAS 2416251-24-4)
- Vancomycin impurity 26 (CAS CATO-C4X-177526)
- Vancomycin impurity 28 (CAS CATO-C4X-177528)
- Vancomycin (CAS 1404-90-6)
- Vancomycin EP Impurity L (CAS 79517-31-0)
- Vancomycin EP Impurity B (CAS 555598-85-1)
- Vancomycin EP Impurity E (CAS 55598-85-1)
Recommended Standards
- Chloroorienticin B (CAS 118373-81-2)
- Perchloro-a,a,a�,a�-tetraphenylbi-p-tolyl-a,a�-ylene biradical (CAS 33135-34-1)
- Mogroside VI (CAS 89590-98-7)
- Iobitridol Impurity 29 (CAS CATO-C4X-317829)
- Agomelatine Impurity N14 (CAS 67247-13-6)
- Epinastine Impurity 42 (CAS CATO-C4X-184042)
- Dexmedetomidine Impurity 71 (CAS 7495-46-7)
- (1-(6-Methoxypyridin-2-yl)cyclopropyl)methanamine dihydrochloride (CAS 1402232-65-8)
- (R)-(-)-1-Phenylethane-1,2-diol (CAS 16355-00-3)
- methyl 3-(6-methoxypyridin-2-yl)-3-oxopropanoate (CAS 1093115-25-3)
- (1-(Phenylsulfonyl)cyclopentyl)methanamine (CAS 1114822-88-6)
- 3-Amino-4-chloro-n-methoxy-n-methylbenzenesulfonamide (CAS 1156152-31-6)
- 4,5,7-Trichloroindoline (CAS 1153392-06-3)
- Semaglutide-d5 (CAS CATO-C4X-2226153)
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