Tenofovir alafenamide impurity 76 CAS CATO-C4X-179776
| CAS No. | CATO-C4X-179776 |
| Molecular Formula | C21H29N6O6P |
| Molecular Weight | 492.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C21H29N6O6P, Tenofovir alafenamide impurity 76 contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 492.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Tenofovir alafenamide impurity 76 (CAS CATO-C4X-179776), a pharmacopoeial impurity reference standard (molecular formula C21H29N6O6P, MW 492.47 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tenofovir alafenamide impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H29N6O6P |
| Molecular Weight | 492.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Tenofovir Standards
- Tenofovir Impurity 28 (CAS 1246812-43-0)
- Tenofovir Amibufenamide (CAS 1571076-26-0)
- Tenofovir disoproxil Impurity 49 (CAS 1244022-56-7)
- Tenofovir Alafenamide-d7 (CAS CATO-C4X-179741)
- Tenofovir Alafenamide-d6 (Mixture of Diastereomers) (CAS CATO-C4X-179739)
- Tenofovir Alafenamide-d6 (R-Phosphine) (CAS CATO-C4X-179740)
- Tenofovir Alafenamide-d5 (Diastereomers) (CAS CATO-C4X-179738)
- Tenofovir disoproxil Impurity 16(See C4X-107650) (CAS CATO-C4X-107616)
Recommended Standards
- Verminoside (CAS 50932-19-9)
- Picroside I (CAS 27409-30-9)
- Methyl 2-(2-{[6-acetyl-3-cyano-4-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl]sulfanyl}acetamido)benzoate (CAS 664999-43-3)
- 5-Acetamido-2-(4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-2-sulfostyryl)benzenesulfonic acid (CAS 118121-38-3)
- Fasudil Impurity 12 (CAS 1211517-62-2)
- Fluticasone Impurity N7 (CAS 80474-27-7)
- Diquafosol Impurity 29 (CAS 22256-98-0（free base）)
- 2-(Methoxyamino)propanoic acid (CAS 54837-08-0)
- 3-(4-Bromophenyl)piperazine-2,5-dione (CAS 1260665-64-2)
- 2-(Difluoromethyl)-3,6-dihydroxypyridine-4-carbonyl chloride (CAS 1805290-51-0)
- (4-Bromo-2-ethylphenyl)methanamine (CAS 877131-68-5)
- Relebactam Impurity 57 (CAS CATO-C4X-214457)
- 4-Iodo-6,6-dimethyl-3,6-dihydro-2H-pyran (CAS 1936544-58-9)
- Semaglutide Impurity 12 (CAS CATO-C4X-222612)
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