Tenofovir Alafenamide-d6 (R-Phosphine) CAS CATO-C4X-179740
| CAS No. | CATO-C4X-179740 |
| Molecular Formula | - |
| Molecular Weight | 482.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tenofovir Alafenamide-d6 (R-Phosphine).
CATO supplies Tenofovir Alafenamide-d6 (R-Phosphine) (CAS CATO-C4X-179740), a certified reference material (molecular formula C21H23D6N6O5P, MW 482.50 g/mol) for analytical method development and quality control.
Owing to deuterium isotope labeling, a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, Tenofovir Alafenamide-d6 (R-Phosphine) is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 482.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H23D6N6O5P |
| Molecular Weight | 482.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Tenofovir Standards
- Tenofovir Alafenamide-d6 (Mixture of Diastereomers) (CAS CATO-C4X-179739)
- Tenofovir Alafenamide-d5 (Diastereomers) (CAS CATO-C4X-179738)
- Tenofovir Alafenamide-d7 (CAS CATO-C4X-179741)
- Tenofovir alafenamide Impurity 33 (CAS CATO-C4X-179733)
- Tenofovir alafenamide Impurity 42 (CAS 2053424-82-9)
- Tenofovir alafenamide Impurity 44 (CAS CATO-C4X-179744)
- Tenofovir alafenamide Impurity 45 (CAS CATO-C4X-179745)
- Tenofovir alafenamide Impurity 52 (CAS 383365-04-6)
Recommended Standards
- N2-(4-(1H-Benzo[d]imidazol-2-yl)phenyl)-N4-(4-fluorophenyl)-6-morpholino-1,3,5-triazine-2,4-diamine (CAS 1807988-47-1)
- GW-328267, >98% (HPLC) (CAS 210237-78-8)
- Fluocinolone Acetonide Impurity 4 (CAS 62013-83-6)
- Cyclohexyl 4-trifluoromethylphenyl ketone (CAS 419543-02-5)
- tert-Butyl (3-hydroxypyridin-2-yl)carbamate (CAS 902835-93-2)
- 7-Oxa-2-azaspiro[3.5]nonane Hydrochloride (CAS 1417633-09-0)
- 2-(Cyclopropyl(2-methylbenzyl)amino)ethanol (CAS 1247474-60-7)
- 2,5-Bis((tert-butoxycarbonyl)amino)benzoic acid (CAS 1260672-05-6)
- 3,4-Dimethyl-5-(m-tolyl)isoxazole (CAS 61314-42-9)
- Methyl 2-amino-4-(pyridin-2-yl)butanoate (CAS 1341582-24-8)
- 3-Ethyl-7-(pyrrolidin-3-yl)quinoline (CAS 695185-28-5)
- Ginsenoside RK2 (CAS 364779-14-6)
- 4-(2-(Thiophen-2-yl)ethoxy)pyridin-2(1H)-one (CAS 1182255-11-3)
- (Ser(PO?H?)3??·???)-Tau Peptide (379-408) trifluoroacetate salt (CAS 2022956-60-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com