Clemastine Impurity 10 Fumarate CAS CATO-C4X-183710
| CAS No. | CATO-C4X-183710 |
| Molecular Formula | C21H27NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Clemastine Impurity 10 Fumarate (CAS CATO-C4X-183710, C21H27NOC4H4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Clemastine Impurity 10 Fumarate (C21H27NOC4H4O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Clemastine Impurity 10 Fumarate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H27NO C4H4O4 |
| Molecular Weight | 425.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Clemastine Standards
- Clemastine Impurity 27 (CAS 10095-17-7)
- Clemastine EP Impurity A(Mixture of Diastereomers) (CAS 108825-05-4)
- Clemastine Impurity 28 (CAS 1333340-87-6)
- Clemastine EP Impurity B (CAS 1352549-49-5)
- Clemastine fumarate (CAS 14976-57-9)
- Clemastine (CAS 15686-51-8)
- Clemastine Impurity 26 (CAS 171296-35-8)
- Clemastine Impurity 4 (CAS 20763-27-3)
Recommended Standards
- Bexagliflozin Impurity 3 (CAS CATO-C4X-33223)
- Betahistine EP Impurity C Trimesilate (CAS CATO-C4X-18383)
- Pazufloxacin Impurity 10 (CAS 165071-09-0)
- 5-Hydroxybenzofuran-2-carboxylic Acid (CAS 56172-36-2)
- Rosuvastatin Impurity 29 (CAS CATO-C4X-116929)
- 4-Bromo-6,7-difluoro-2-methylisoquinolin-1(2H)-one (CAS 2755695-51-1)
- 4-Cyclopropoxy-6-ethylpyridine-3-sulfonamide (CAS 1243467-03-9)
- (2-(4-Nitrophenoxy)phenyl)methanol (CAS 25562-37-2)
- Methyl 2-ethyl-3-oxo-2,3-dihydropyridazine-4-carboxylate (CAS 1710846-15-3)
- Semaglutide Impurity 163 (x TFA Salt) (CAS CATO-C4X-2226163)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com