Clemastine Impurity 9 CAS CATO-C4X-18379
| CAS No. | CATO-C4X-18379 |
| Molecular Formula | C21H27NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Clemastine Impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Clemastine Impurity 9 (CAS CATO-C4X-18379, C21H27NOC4H4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Clemastine Impurity 9 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 425.52 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C21H27NO C4H4O4 |
| Molecular Weight | 425.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Clemastine Standards
- Clemastine Impurity 27 (CAS 10095-17-7)
- Clemastine EP Impurity A(Mixture of Diastereomers) (CAS 108825-05-4)
- Clemastine Impurity 28 (CAS 1333340-87-6)
- Clemastine EP Impurity B (CAS 1352549-49-5)
- Clemastine fumarate (CAS 14976-57-9)
- Clemastine (CAS 15686-51-8)
- Clemastine Impurity 26 (CAS 171296-35-8)
- Clemastine Impurity 4 (CAS 20763-27-3)
Recommended Standards
- Amlodipine Impurity 100 (CAS CATO-C4X-1095100)
- Opicapone impurity 31 (CAS CATO-C4X-240431)
- Oxybutynin Impurity 11 HCl (CAS 1199574-71-4 (free base))
- 2-Methyl-1-(3-(trifluoromethyl)phenyl)propan-1-one (CAS 586369-93-9)
- Diphenyl Phthalate-3,4,5,6-d4 (CAS 1398065-61-6)
- L-(+)-N-[p-[[(2-Amino-7,8-dihydro-4-hydroxy-6-pteridinyl)methyl]nitrosamino]benzoyl]-glutamic Acid (CAS 15574-33-1)
- 2-(4-Amino-2h-1,2,3-triazol-2-yl)acetic acid (CAS 1368124-71-3)
- Milrinone Impurity 34 (CAS 1089899-00-2)
- Sildenafil Impurity 16 (CAS 1971915-89-5)
- 141801-03-8 IL-1 Receptor Peptide (human) (CAS 141801-03-8)
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