Bosutinib Impurity 16 CAS CATO-C4X-184716
| CAS No. | CATO-C4X-184716 |
| Molecular Formula | C26H31Cl2N5O4 |
| Molecular Weight | 548.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Bosutinib Impurity 16 (CAS CATO-C4X-184716), a pharmacopoeial impurity reference standard (molecular formula C26H31Cl2N5O4, MW 548.46 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Bosutinib Impurity 16 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 548.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Bosutinib Impurity 16 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H31Cl2N5O4 |
| Molecular Weight | 548.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Bosutinib Standards
- Bosutinib Impurity 17 (CAS CATO-C4X-184717)
- Bosutinib Impurity 2 (CAS CATO-C4X-18472)
- Bosutinib Impurity 38 (CAS CATO-C4X-184738)
- Bosutinib Impurity 37 (CAS CATO-C4X-184737)
- Bosutinib Impurity 35 (CAS CATO-C4X-184735)
- Bosutinib Impurity 31 (CAS CATO-C4X-184731)
- Bosutinib Methanoate (CAS 918639-10-8)
- bosutinib (CAS 380843-75-4)
Recommended Standards
- t-Boc-Aminooxy-PEG7-bromide (CAS 2353410-15-6)
- Rimegepant Impurity 7 (CAS CATO-C4X-24877)
- 3,3'-(Oxybis(1,3-dioxoisoindoline-5,2-diyl))dibenzoic acid (CAS 304871-39-4)
- Sitagliptin Impurity N53 (CAS 2379621-81-3)
- Topiramate Impurity 13 (CAS 86569-78-0)
- Tedizolid Impurity 72 (CAS CATO-C4X-105472)
- Salbutamol EP Impurity D(Formic Acid) (CAS 156339-88-7（free base）)
- 5'h,7'h-Spiro[cyclobutane-1,6'-pyrazolo[5,1-b][1,3]oxazin]-3'-amine hydrochloride (CAS 2251053-34-4)
- 3-Bromo-6-ethyl-7-methoxy-5-methylpyrazolo[1,5-a]pyrimidine (CAS 1429309-29-4)
- O-Ethyl O-(3,5,6-trichloropyridin-2-yl) O-hydrogen phosphorothioate (CAS 66651-96-5)
- Naphthalen-1-ylmethyl-hydrazine (CAS 51421-38-6)
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- 4-Fluoro-2-(2-methylallyl)-phenol (CAS 948294-29-9)
- D-[His]1-Semaglutide X TFA salt (CAS CATO-CPTD788634)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com