Arotinolol impurity 24 CAS CATO-C4X-185424
| CAS No. | CATO-C4X-185424 |
| Molecular Formula | C7H5Br2NO2S |
| Molecular Weight | 326.99 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Arotinolol impurity 24 (CAS CATO-C4X-185424), a pharmacopoeial impurity reference standard (molecular formula C7H5Br2NO2S, MW 326.99 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system, Arotinolol impurity 24 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 326.99 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Arotinolol impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5Br2NO2S |
| Molecular Weight | 326.99 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Arotinolol Standards
- Arotinolol Impurity 78 (CAS CATO-C4X-185478)
- Arotinolol Impurity 21 (CAS CATO-C4X-185421)
- Arotinolol Impurity 73 (CAS CATO-C4X-185473)
- Arotinolol Impurity 14 (CAS 1701418-50-9)
- Arotinolol Impurity 79 (CAS CATO-C4X-185479)
- Arotinolol Impurity 57 (CAS CATO-C4X-185457)
- Arotinolol Impurity 53 (CAS CATO-C4X-185453)
- Arotinolol Impurity 60 (CAS CATO-C4X-185460)
Recommended Standards
- 6-Bromo-1,1,1,2,2,3,3,4,4-nonafluorohexane (CAS 38436-14-5)
- Rubber Oligomer Impurity 6 (CAS 2446375-29-5)
- 4-Bromomethoxy-2,3,5,6-tetrafluorobenzotrifluoride (CAS 883521-27-5)
- 2-Bromo-6,9-dichloroacridine (CAS 62383-20-4)
- Decitabine Impurity 11 (CAS CATO-C4X-113711)
- Amiodarone Impurity 18 (CAS 23349-86-2)
- Lumefantrine Impurity 4 (CAS 1795128-25-4)
- Tert-butyl 2-(2-methoxy-2-oxo-1-phenylethyl)pyrazolidine-1-carboxylate (CAS 952183-21-0)
- 1-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-amine (CAS 1251264-73-9)
- 2-Acetylnaphthalene-1,4-dione (CAS 5813-57-0)
- Calcipotriol EP Impurity C (CAS 113082-99-8)
- Ethyl 2-amino-2-(tetrahydro-2H-pyran-4-yl)acetate (CAS 646055-93-8)
- 8-(4-Methoxyphenyl)-1,4-dioxaspiro[4.5]Decan-8-ol (CAS 67019-51-6)
- Semaglutide impurity 41 (CAS CATO-C4X-222641)
Why CATO?
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