Tigecycline Impurity 34 CAS CATO-C4X-186034
| CAS No. | CATO-C4X-186034 |
| Molecular Formula | C25H29ClN4O8 |
| Molecular Weight | 548.97 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Tigecycline Impurity 34 (CAS CATO-C4X-186034, C25H29ClN4O8) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Tigecycline Impurity 34 (C25H29ClN4O8) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C25H29ClN4O8 |
| Molecular Weight | 548.97 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Tigecycline Standards
- Tigecycline Impurity 5 (CAS CATO-C4X-18605)
- Tigecycline Impurity 7 (CAS 1268494-40-1)
- Tigecycline Impurity 32 (CAS CATO-C4X-186032)
- Tigecycline Impurity 9 (CAS 1268494-46-7)
- Tigecycline Impurity 3 (CAS CATO-C4X-18603)
- Tigecycline Impurity 2 (CAS CATO-C4X-18602)
- Tigecycline Impurity N1 (CAS 1633815-62-9)
- Tigecycline Impurity 33 (CAS CATO-C4X-186033)
Recommended Standards
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- Latamoxef Impurity 25 (CAS CATO-C4X-179825)
- Nafamostat Impurity 19 (CAS 63101-32-6)
- Nemonoxacin Impurity 74 (CAS CATO-C4X-312874)
- Parecoxib Impurity 54 (CAS CATO-C4X-159154)
- tert-Butyl (S)-3-((methylsulfonyl)methyl)piperazine-1-carboxylate (CAS 2655731-42-1)
- Spiro[2.5]Octane-4-carboxylic acid (CAS 83115-72-4)
- 2-(3,5-Dimethoxyphenyl)-4-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridazin-3(2H)-one (CAS 2095780-23-5)
- 1,10-diazatricyclo[6.4.1.0^{4,13}]trideca-2,4(13),5,7-tetraene (CAS 27158-93-6)
- 2,2,4-Trimethylpent-4-enoic acid (CAS 56001-56-0)
- 5-(2,3-Difluorophenyl)nicotinamide (CAS 1346691-63-1)
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