Etomidate impurity 67 CAS CATO-C4X-188467
| CAS No. | CATO-C4X-188467 |
| Molecular Formula | C11H15NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 229.70 g/mol gives Etomidate impurity 67 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Etomidate impurity 67 (CAS CATO-C4X-188467) is a certified pharmaceutical impurity reference standard with the molecular formula C11H15NO2HCl and a molecular weight of 229.70 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Etomidate impurity 67 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 229.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Etomidate impurity 67 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H15NO2 HCl |
| Molecular Weight | 229.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Etomidate Standards
- Etomidate Impurity 23 (CAS 112421-33-7)
- Etomidate Racemate (CAS 15301-65-2)
- Etomidate Impurity 75 (CAS 1567838-90-7)
- Etomidate Impurity 6 (CAS 23785-21-9)
- Etomidate Impurity N15 (CAS 2433776-55-5)
- Etomidate Impurity 50 (CAS 2626887-15-6)
- Etomidate Impurity N3 (CAS 31502-34-8)
- Etomidate EP Impurity A (CAS 3157-27-5)
Recommended Standards
- Eplerenone Impurity 25 (CAS CATO-C4X-163025)
- Ziprasidone EP Impurity E (CAS 1159977-04-4)
- Remdesivir Impurity 36 (CAS CATO-C4X-210036)
- 2-methylimidazo[1,2-a]pyridine-6-carboxylic acid (CAS 129912-22-7)
- 2-(6-(Aminomethyl)pyridin-2-yl)propan-2-ol (CAS 1202403-02-8)
- Tripropylsilyl chloride (CAS 995-25-5)
- 2-Chloro-6-methoxy-4-methylquinolin-8-amine (CAS 74509-63-0)
- Fluticasone Furoate EP Impurity I (CAS 3086156-07-9)
- 1-(4-Methoxyphenyl)-3-(m-tolyl)-1H-pyrazol-5-amine (CAS 618098-10-5)
- Tau Peptide (268-282) trifluoroacetate salt (CAS 330456-37-6)
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