Esmolol Impurity 68 CAS CATO-C4X-189168
| CAS No. | CATO-C4X-189168 |
| Molecular Formula | C16H24N2O5 |
| Molecular Weight | 324.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Esmolol Impurity 68 (CAS CATO-C4X-189168, C16H24N2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Esmolol Impurity 68 (C16H24N2O5) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Esmolol Impurity 68 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H24N2O5 |
| Molecular Weight | 324.37 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Esmolol Standards
- Esmolol Impurity 92 (CAS CATO-C4X-189192)
- Esmolol Impurity 43 (CAS CATO-C4X-189143)
- Esmolol Impurity 83 (CAS CATO-C4X-189183)
- Esmolol Impurity 5 (CAS 83356-59-6)
- Esmolol Impurity 44 (CAS CATO-C4X-189144)
- Esmolol Impurity 42 (CAS CATO-C4X-189142)
- Esmolol Impurity 36 (CAS CATO-C4X-189136)
- Esmolol Impurity 72 (CAS 1293388-71-2)
Recommended Standards
- Dolasetron Impurity 1 (CAS CATO-C4X-18671)
- Acetylcysteine EP Impurity C (CAS 5545-17-5)
- Proparacaine Impurity 36 (CAS CATO-C4X-202736)
- Tiopronin Impurity 1 (CAS 21269-37-4)
- Estradiol Impurity 49 (CAS CATO-C4X-163649)
- Metoclopramide Impurity 76 (CAS CATO-C4X-141576)
- Peramivir Impurity 2 (CAS 344326-33-6)
- (5-amino-1,3-benzoxazol-2-yl)methanol (CAS 948306-37-4)
- Asciminib Impurity N1 (CAS 1492952-73-4)
- 4-Chloro-N-((5-((4-chlorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)methyl)benzenesulfonamide (CAS 338421-95-7)
- 4-bromo-5-methyl-1,3-benzothiazol-2-amine (CAS 1427373-92-9)
- 6-Methyl-[1,2,4]triazolo[4,3-b]pyridazine (CAS 18591-78-1)
- Azinphos-Methyl (CAS 86-50-0)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
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