Nicorandil impurity 61 CAS CATO-C4X-190761
| CAS No. | CATO-C4X-190761 |
| Molecular Formula | C15H17NO2 |
| Molecular Weight | 243.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Nicorandil impurity 61 (C15H17NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a process- or degradation-related impurity, Nicorandil impurity 61 (CAS CATO-C4X-190761, C15H17NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Nicorandil impurity 61 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H17NO2 |
| Molecular Weight | 243.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Nicorandil Standards
- Nicorandil impurity 60 (CAS CATO-C4X-190760)
- Nicorandil Impurity 56 (CAS CATO-C4X-190756)
- Nicorandil Impurity 18 (CAS CATO-C4X-190718)
- Nicorandil N-Oxide (CAS 107833-98-7)
- Nicorandil Impurity 7 (CAS 113743-17-2)
- Nicorandil Impurity 28 (CAS 34104-46-6)
- Nicorandil-d4 (CAS 1132681-23-2)
- Nicorandil Impurity 55 (CAS 3612-79-1)
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com