Fulvestrant Impurity 14 CAS CATO-C4X-191714
| CAS No. | CATO-C4X-191714 |
| Molecular Formula | C32H45Br2F5O3S |
| Molecular Weight | 764.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Fulvestrant Impurity 14 (C32H45Br2F5O3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Fulvestrant Impurity 14 (CAS CATO-C4X-191714) is a certified pharmaceutical impurity reference standard with the molecular formula C32H45Br2F5O3S and a molecular weight of 764.56 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C32H45Br2F5O3S |
| Molecular Weight | 764.56 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Br-containing |
| Sulfur Atoms | 1 |
Related Fulvestrant Standards
- Fulvestrant Impurity 37 (CAS 148757-89-5)
- Fulvestrant impurity 57 (CAS CATO-C4X-191757)
- Fulvestrant EP Impurity C (CAS CATO-C4X-19173)
- Fulvestrant impurity 34 (CAS CATO-C4X-191734)
- Fulvestrant-17-Glucuronide (CAS 261506-28-9)
- Fulvestrant-3-Glucuronide (CAS 261506-27-8)
- Fulvestrant impurity 54 (CAS CATO-C4X-191754)
- Fulvestrant Impurity 12 (CAS CATO-C4X-191712)
Recommended Standards
- Chloro[tris(2,3,4,5,6-pentafluorophenyl)phosphine-κP]gold (CAS 37095-26-4)
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- Dichloro(3-methyl-2-butenylidene)bis(triphenylphosphine)ruthenium (CAS 191609-95-7)
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- Eltrombopag Impurity 52 (CAS CATO-C4X-119852)
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- Baricitinib Impurity 22 (CAS 2075-45-8)
- Ropivacaine Impurity 14 (CAS 826-99-3)
- tert-Butyl (S)-4-(aminomethyl)-2,2-dimethyloxazolidine-3-carboxylate (CAS 1186497-83-5)
- 2-Chloro-3,6-difluorobenzenesulfonyl chloride (CAS 1208074-71-8)
- trans-(2-Aminocyclohexyl)methanol (CAS 5691-21-4)
- (2-(2-Aminoethyl)piperidin-1-yl)(5-methyl-1h-pyrazol-3-yl)methanone (CAS 1839512-97-8)
- 3-Bromo-5-(pentafluoro-λ6-sulfanyl)benzoic acid (CAS 1180675-98-2)
- Palmitoyl hexapeptide-6 (CAS 891498-01-4)
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