Doxorubicin Impurity 30 CAS CATO-C4X-203330
| CAS No. | CATO-C4X-203330 |
| Molecular Formula | C27H26Br3NO10 |
| Molecular Weight | 764.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Doxorubicin Impurity 30 (C27H26Br3NO10) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Doxorubicin Impurity 30 (CAS CATO-C4X-203330, C27H26Br3NO10) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Doxorubicin Impurity 30 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H26Br3NO10 |
| Molecular Weight | 764.21 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Doxorubicin Standards
- Doxorubicin-hydrazone-caproyl-maleimide (CAS 151038-96-9)
- Doxorubicin Impurity 27 (CAS CATO-C4X-203327)
- Doxorubicin Impurity N19 (CAS 106401-68-7)
- Doxorubicin Impurity 25 (CAS CATO-C4X-203325)
- Doxorubicin Impurity 28 (CAS CATO-C4X-203328)
- Doxorubicin Impurity 33 (CAS CATO-C4X-203333)
- Doxorubicin Impurity 9 (CAS CATO-C4X-20339)
- Doxorubicin (CAS 23214-92-8)
Recommended Standards
- 1H,1H,2H,2H-Perfluorohexadecan-1-ol (CAS 60699-51-6)
- Fulvestrant Impurity 37 (CAS 148757-89-5)
- 5,5',5'',5'''-Silanetetrayltetrakis(2-bromobenzaldehyde) (CAS 1544168-58-2)
- Chloro[tris(2,3,4,5,6-pentafluorophenyl)phosphine-κP]gold (CAS 37095-26-4)
- Bexarotene Impurity 2 (CAS CATO-C4X-29502)
- Revefenacin Impurity 26 (CAS 108015-71-0)
- Carfilzomib Impurity 72 (CAS CATO-C4X-102272)
- 5-((Benzo[d][1,3]dioxol-5-ylmethyl)amino)-5-oxopentanoic acid (CAS 438530-15-5)
- Methyl 2-amino-2-(4-chloro-3-fluorophenyl)acetate (CAS 1249711-69-0)
- Dihydropyrocurzerenone (CAS 59462-26-9)
- 3-(Dimethylamino)-1-phenyl-2,3-dihydroquinazolin-4(1H)-one (CAS 90071-01-5)
- [1,2,4]Triazolo[1,5-a]pyrazine-8-carbonitrile (CAS 86805-31-4)
- [1,3-Bis[2,6-bis(diphenylmethyl)-4-methylphenyl]-1,3-dihydro-2H-imidazol-2-ylidene]hydroxygold-HF (CAS 1690356-92-3)
- Semaglutide-d15 (CAS 910463-68-2(non-labelled))
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