Methylprednisolone EP Impurity D(E-Isomer) CAS CATO-C4X-19194
| CAS No. | CATO-C4X-19194 |
| Molecular Formula | C22H28O4 |
| Molecular Weight | 356.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Methylprednisolone EP Impurity D(E-Isomer) (CAS CATO-C4X-19194) is a certified pharmaceutical impurity reference standard with the molecular formula C22H28O4 and a molecular weight of 356.46 g/mol.
Methylprednisolone EP Impurity D(E-Isomer) (C22H28O4) contains a flavonoid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Methylprednisolone EP Impurity D(E-Isomer) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H28O4 |
| Molecular Weight | 356.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Methylprednisolone Standards
- Methylprednisolone EP Impurity D (CAS 1338549-02-2)
- Methylprednisolone EP Impurity G (CAS 93269-35-3)
- Methylprednisolone Impurity 79 (CAS CATO-C4X-191979)
- Methylprednisolone impurity 6 (CAS CATO-C4X-191986)
- Methylprednisolone Acetate EP Impurity I (CAS 6870-94-6)
- Methylprednisolone Impurity 57 (CAS 1048031-80-6)
- Methylprednisolone Impurity 81 (CAS 82332-00-1)
- Methylprednisolone EP Impurity E (CAS 229019-44-7)
Recommended Standards
- Thiamine nitrate EP Impurity H (CAS 89285-03-0)
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- Orforglipron Impurity 41 (CAS CATO-C4X-323441)
- Midazolam Impurity 29 (CAS CATO-C4X-150929)
- Flurbiprofen Impurity 73 (CAS CATO-C4X-144473)
- Amisulpride Impurity 22 (CAS 1823413-49-5)
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Why CATO?
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