Methylprednisolone Impurity 70 CAS CATO-C4X-191970
| CAS No. | CATO-C4X-191970 |
| Molecular Formula | C22H28O5 |
| Molecular Weight | 372.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methylprednisolone Impurity 70.
CATO supplies Methylprednisolone Impurity 70 (CAS CATO-C4X-191970), a pharmacopoeial impurity reference standard (molecular formula C22H28O5, MW 372.45 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Methylprednisolone Impurity 70 (C22H28O5) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H28O5 |
| Molecular Weight | 372.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Methylprednisolone Standards
- Methylprednisolone Acetate EP Impurity C (CAS 58636-50-3)
- Methylprednisolone EP Impurity A (CAS 91523-05-6)
- Methylprednisolone Impurity 62 (CAS 95810-22-3)
- Methylprednisolone Impurity 37 (CAS 1746-38-9)
- Methylprednisolone EP Impurity H (CAS 18462-27-6)
- Methylprednisolone impurity 82 (CAS 106502-98-1)
- Methylprednisolone impurity 87 (CAS 105500-05-8)
- 6-Alpha-Methylprednisolone (CAS 83-43-2)
Recommended Standards
- 7-TMCA Impurity 3 (CAS CATO-C4X-23183)
- Meprednisone (CAS 1247-42-3)
- Ulipristal Impurity 14 (CAS CATO-C4X-191514)
- Pyrethrin 2 (CAS 121-29-9)
- Trametinib impurity 18 (CAS 1383430-03-2)
- Glycerol Impurity 41 (CAS 42320-97-8)
- Linezolid Impurity 70 (CAS CATO-C4X-107370)
- 1-(Ethoxymethyl)-1H-pyrrole-2-carbonyl chloride (CAS 714957-07-0)
- 1-Methoxy-1-(trimethylsiloxy)-2-methyl-1-propene (CAS 17878-39-6)
- 2-Isopropyl-1-(3-nitrobenzyl)-1H-imidazole (CAS 1171517-76-2)
- 1-(1-Methylpiperidin-4-yl)-5-oxopyrrolidine-3-carboxylic acid (CAS 933691-56-6)
- Naginata ketone (CAS 6138-88-1)
- (2-Boc-amino-pyridin-4-yl)-acetic acid methyl ester (CAS 1260890-57-0)
- Liraglutide(5-31)TFA Salt (CAS CATO-C4X-19924)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com