Pimavanserin Impurity 22 CAS CATO-C4X-193822
| CAS No. | CATO-C4X-193822 |
| Molecular Formula | C22H31NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 377.95 g/mol gives Pimavanserin Impurity 22 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Pimavanserin Impurity 22 (CAS CATO-C4X-193822) is a certified pharmaceutical impurity reference standard with the molecular formula C22H31NO2HCl and a molecular weight of 377.95 g/mol.
The molecular framework of Pimavanserin Impurity 22 (C22H31NO2HCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H31NO2 HCl |
| Molecular Weight | 377.95 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Pimavanserin Standards
- Pimavanserin Impurity 2 (CAS 103907-97-7)
- Pimavanserin Impurity 1 (CAS 107456-06-4)
- Pimavanserin Impurity 20 (CAS 1134815-71-6)
- Pimavanserin Impurity 46 (CAS 1173710-95-6)
- Pimavanserin Impurity 51 (CAS 13221-89-1)
- Pimavanserin Acid Impurity (CAS 13362-94-2)
- Pimavanserin Impurity 3 (CAS 134227-41-1)
- Pimavanserin Impurity 35 (CAS 1791227-69-4)
Recommended Standards
- Tadalafil Impurity 119 (CAS CATO-C4X-1087119)
- Ruxolitinib Impurity 8 (CAS 2606144-45-8)
- Idebenone Impurity 3 (CAS CATO-C4X-30163)
- 1-Phenyloctan-1-amine hydrochloride (CAS 92330-57-9)
- Proxyphylline impurity 10 (CAS CATO-C4X-244010)
- (R)-2-(1-Imidazolyl)propanoic Acid (CAS 754145-95-4)
- 1-(3-Chloropyridin-4-yl)ethanone (CAS 78790-82-6)
- 1-Isopropyl-4-(naphthalen-1-yl)-1H-pyrazole (CAS 1394023-01-8)
- 1-Methyl-2-(pyrrolidin-1-ylmethyl)-1H-benzo[d]imidazol-5-amine (CAS 1091699-88-5)
- Des-Ala21-Tirzepatide (CAS CATO-CPTD788952)
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