Pimavanserin impurity 59 CAS CATO-C4X-193859
| CAS No. | CATO-C4X-193859 |
| Molecular Formula | C13H18FN3O |
| Molecular Weight | 251.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Pimavanserin impurity 59 (CAS CATO-C4X-193859) is a certified pharmaceutical impurity reference standard with the molecular formula C13H18FN3O and a molecular weight of 251.30 g/mol.
The molecular framework of Pimavanserin impurity 59 (C13H18FN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H18FN3O |
| Molecular Weight | 251.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Pimavanserin Standards
- Pimavanserin Impurity 46 (CAS 1173710-95-6)
- Pimavanserin Impurity 37 (CAS CATO-C4X-193837)
- Pimavanserin Impurity 38 (CAS CATO-C4X-193838)
- Pimavanserin Impurity 52 (CAS CATO-C4X-193852)
- Pimavanserin Impurity 3 (CAS 134227-41-1)
- Pimavanserin Impurity 17 (CAS CATO-C4X-193817)
- Pimavanserin Impurity 4 (CAS 428819-12-9)
- Pimavanserin Impurity 1 (CAS 107456-06-4)
Recommended Standards
- Rasagiline Impurity 5 (CAS CATO-C4X-19135)
- Carbocisteine Impurity 32 (CAS CATO-C4X-201032)
- Linezolid Impurity 19 (CAS CATO-C4X-153519)
- Carboxymethylstane Propylene Glycol Ester (CAS CATO-C4X-201033)
- Tizanidine Impurity 38 (CAS CATO-C4X-144538)
- Imrecoxib Impurity 79 (CAS CATO-C4X-237979)
- Clevidipine Impurity C41 (CAS 1898262-46-8)
- Bis(9-ethyl-9H-carbazol-3-yl)diphenylsilane (CAS 18845-50-6)
- 3-Benzyl-7-chloro-2-(pyrrolidin-2-yl)quinazolin-4(3H)-one (CAS 681827-24-7)
- 4-(Difluoromethyl)-6-methoxy-3-methylpyridine-2-sulfonyl chloride (CAS 1805439-10-4)
- Isopropyl Diphenyl Phosphate (CAS 60763-39-5)
- 3-(2-Aminoacetamido)propanamide hydrochloride (CAS 3816-80-6)
- 4-(chloromethyl)-2-propyl-1,3-thiazole (CAS 40516-58-3)
- Liraglutide(14-22)TFA Salt (CAS CATO-C4X-199212)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com