Latanoprost Impurity 28 CAS CATO-C4X-194128
| CAS No. | CATO-C4X-194128 |
| Molecular Formula | C26H34O5 |
| Molecular Weight | 426.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Latanoprost Impurity 28 (CAS CATO-C4X-194128, C26H34O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Latanoprost Impurity 28 (C26H34O5) contains a steroid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 426.55 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H34O5 |
| Molecular Weight | 426.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Latanoprost Standards
- Latanoprost Impurity 15 (CAS CATO-C4X-194115)
- Latanoprost Impurity 14 (CAS CATO-C4X-194114)
- Latanoprost Impurity 30 (CAS CATO-C4X-194130)
- Latanoprost Impurity 19 (CAS CATO-C4X-194119)
- Latanoprost EP Impurity E (CAS 145773-22-4)
- Latanoprost EP Impurity F (CAS 913258-34-1)
- Latanoprost (CAS 130209-82-4)
- 2-Nor Latanoprost (CAS CATO-C4X-19414)
Recommended Standards
- Beraprost Impurity 6 (Mixture of Diastereomers) (CAS CATO-C4X-21846)
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- Ibuprofen Impurity 67 (CAS CATO-C4X-108267)
- Ammoxetine Impurity 19 (CAS CATO-C4X-335719)
- Baloxavir Impurity 45 (CAS 2571566-81-7)
- Ruilugoli lmpurity 133 (CAS CATO-C4X-2429133)
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- Ethyl 2-((4-chlorophenyl)thio)acetate (CAS 52377-68-1)
- 1-(6-(4-Ethylpiperazin-1-yl)-2-methylpyridin-3-yl)ethanamine (CAS 1355174-50-3)
- D-[Ser]8-Liraglutide (CAS CATO-C4X-199238)
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