Granisetron Impurity 14 CAS CATO-C4X-197014
| CAS No. | CATO-C4X-197014 |
| Molecular Formula | C18H22N4O2 |
| Molecular Weight | 326.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Granisetron Impurity 14 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Granisetron Impurity 14 (CAS CATO-C4X-197014), a pharmacopoeial impurity reference standard (molecular formula C18H22N4O2, MW 326.39 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Granisetron Impurity 14 (C18H22N4O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 326.39 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H22N4O2 |
| Molecular Weight | 326.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Granisetron Standards
- Granisetron Impurity 19 (CAS CATO-C4X-197019)
- Granisetron Impurity 21 (CAS CATO-C4X-197021)
- Granisetron N-Oxide (CAS 160177-68-4)
- Granisetron EP Impurity I (CAS 1363173-34-5)
- Granisetron-d3 (CAS 1224925-76-1)
- Granisetron EP Impurity A (CAS 127472-42-8)
- Granisetron (CAS 109889-09-0)
- Granisetron Impurity 20 (CAS CATO-C4X-197020)
Recommended Standards
- Dolasetron Impurity 3 (CAS CATO-C4X-18673)
- Dehydrodiisoeugenol (CAS 2680-81-1)
- Dolasetron Impurity 2 (CAS 127951-99-9)
- Eugenol EP Impurity M (CAS 4433-08-3)
- Canagliflozin Impurity 93 (CAS CATO-C4X-112393)
- Creatine Phosphate Impurity 4 (CAS CATO-C4X-12094)
- Resmetirom Impurity 13 (CAS CATO-C4X-291213)
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