Granisetron N-Oxide CAS 160177-68-4
| CAS No. | 160177-68-4 |
| Molecular Formula | C18H24N4O2 |
| Molecular Weight | 328.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Granisetron N-Oxide.
CATO supplies Granisetron N-Oxide (CAS 160177-68-4), a certified reference material (molecular formula C18H24N4O2, MW 328.41 g/mol) for analytical method development and quality control.
Granisetron N-Oxide (C18H24N4O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Granisetron N-Oxide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H24N4O2 |
| Molecular Weight | 328.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Nitrogen Atoms | 4 |
Related Granisetron Standards
- Granisetron Impurity 19 (CAS CATO-C4X-197019)
- Granisetron Impurity 21 (CAS CATO-C4X-197021)
- Granisetron Impurity 14 (CAS CATO-C4X-197014)
- Granisetron EP Impurity I (CAS 1363173-34-5)
- Granisetron-d3 (CAS 1224925-76-1)
- Granisetron Impurity 20 (CAS CATO-C4X-197020)
- Granisetron EP Impurity A (CAS 127472-42-8)
- Granisetron (CAS 109889-09-0)
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Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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