Ivermectin EP Impurity J CAS CATO-C4X-198220
| CAS No. | CATO-C4X-198220 |
| Molecular Formula | C47H72O14 |
| Molecular Weight | 861.07 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ivermectin EP Impurity J is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ivermectin EP Impurity J (CAS CATO-C4X-198220) is a certified pharmaceutical impurity reference standard with the molecular formula C47H72O14 and a molecular weight of 861.07 g/mol.
Structurally, Ivermectin EP Impurity J (C47H72O14) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 861.07 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C47H72O14 |
| Molecular Weight | 861.07 g/mol |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Ivermectin Standards
- Ivermectin B1b (CAS 70209-81-3)
- Ivermectin EP Impurity A (CAS 65195-55-3)
- Ivermectin EP Impurity F (CAS CATO-C4X-198213)
- Ivermectin EP Impurity I(Mixture of Diastereomers) (CAS 1135339-49-9)
- Ivermectin impurity 22 (CAS CATO-C4X-198222)
- Ivermectin EP Impurity I (4S-Isomer) (CAS CATO-C4X-19829)
- Ivermectin B1a (CAS 71827-03-7)
- Ivermectin EP Impurity K (CAS 74567-01-4)
Recommended Standards
- 3"-O-Demethyl Ivermectin (CAS 92137-95-6)
- ((1S)-3,3'-Bis(((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)oxy)-6,6'-dimethoxy-[1,1'-biphenyl]-2,2'-diyl)bis(diphenylphosphine) (CAS 716376-58-8)
- Carfilzomib Impurity 94 (CAS CATO-C4X-102294)
- 2'-O-TBDMS-Pseudouridine (CAS 163496-23-9)
- Regadenoson Impurity 35 (CAS CATO-C4X-198535)
- Aprepitant impurity 55 (CAS CATO-C4X-114155)
- Tafluprost 16E-Diene Impurity(Discontinued,See C4X-216310) (CAS CATO-C4X-21631)
- 4-Methylpiperazin-1-amine dihydrochloride (CAS 40675-60-3)
- Ethyl 2-(2-oxopyridin-1(2H)-yl)propanoate (CAS 1446704-75-1)
- 2-(2-Morpholinoethyl)-6-phenyl-4-(3-(trifluoromethyl)phenyl)pyridazin-3(2H)-one (CAS 23348-47-2)
- 1-chloro-3-[(1-methoxypropan-2-yl)oxy]propan-2-ol (CAS 1564601-58-6)
- [1-(2,2,2-Trifluoroethyl)azetidin-3-yl]methanol (CAS 1498106-29-8)
- Monomagnesium bis((S)-2-aminosuccinate) tetrahydrate (CAS 7018-07-7)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
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