Vinblastine impurity 8 CAS CATO-C4X-19848
| CAS No. | CATO-C4X-19848 |
| Molecular Formula | C46H58N4O10 |
| Molecular Weight | 826.97 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 826.97 g/mol gives Vinblastine impurity 8 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Vinblastine impurity 8 (CAS CATO-C4X-19848), a pharmacopoeial impurity reference standard (molecular formula C46H58N4O10, MW 826.97 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Vinblastine impurity 8 (C46H58N4O10) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Vinblastine impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C46H58N4O10 |
| Molecular Weight | 826.97 g/mol |
| Purity | 90+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Vinblastine Standards
- Vinblastine impurity 7 (CAS CATO-C4X-19847)
- Vinblastine impurity 6 (CAS CATO-C4X-19846)
- Vinblastine impurity A (CAS CATO-C4X-19845)
- Vinblastine Impurity 10 (CAS 55855-88-4)
- 6b-Vinblastine (CAS 363623-08-9)
- VINBLASTINE SULFATE (CAS 1212440-53-3)
- Vinblastine-d3 Sulfate (CAS 1246818-72-3)
- Vinblastine Sulfate (CAS 143-67-9)
Recommended Standards
- Vincristine Impurity 18 (CAS CATO-C4X-208918)
- Magnolianin (CAS 147663-91-0)
- Telithromycin impurity 1 (CAS CATO-C4X-27601)
- EsculentosideA (CAS 65497-07-6)
- Fesoterodine Impurity 13 (CAS 1333234-71-1)
- Bortezomib Impurity 48（1R,2R） (CAS CATO-C4X-107248)
- Neostigmine impurity 40 (CAS CATO-C4X-204240)
- 2-(4-Oxothieno[2,3-d][1,2,3]triazin-3(4H)-yl)acetic acid (CAS 1708428-18-5)
- 2-chloro-N-ethyl-N-[2-(ethylamino)-2-oxoethyl]acetamide (CAS 923225-22-3)
- 2-Chloro-5-methoxy-[1,3]thiazolo[5,4-b]pyridine (CAS 1196154-04-7)
- 5-((5-Amino-4-((2-aminoethyl)amino)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CAS 1137475-62-7)
- tert-Butyl 2-(6-bromopyridin-3-yl)piperidine-1-carboxylate (CAS 1352508-40-7)
- Methyl 4-(2-((5-((naphthalen-1-yloxy)methyl)-1,3,4-oxadiazol-2-yl)thio)acetamido)benzoate (CAS 332161-25-8)
- C-Peptide（dog） (CAS 39016-05-2)
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