Bumetanide Impurity 126 CAS CATO-C4X-1986126
| CAS No. | CATO-C4X-1986126 |
| Molecular Formula | C8H7ClN2O6S |
| Molecular Weight | 294.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Bumetanide Impurity 126 (CAS CATO-C4X-1986126) is a certified pharmaceutical impurity reference standard with the molecular formula C8H7ClN2O6S and a molecular weight of 294.67 g/mol.
Based on its molecular formula C8H7ClN2O6S, Bumetanide Impurity 126 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 294.67 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Bumetanide Impurity 126 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7ClN2O6S |
| Molecular Weight | 294.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bumetanide Standards
- Bumetanide Impurity 68 (CAS CATO-C4X-198668)
- Bumetanide Impurity 50 (CAS 37531-34-3)
- Bumetanide Impurity 42 (CAS 320417-11-6)
- Bumetanide Impurity 32 (CAS 22892-95-1)
- Bumetanide Impurity 16 (CAS CATO-C4X-198616)
- Bumetanide Impurity 66 (CAS CATO-C4X-198666)
- Bumetanide Impurity 57 (CAS CATO-C4X-198657)
- Bumetanide Impurity 65 (CAS CATO-C4X-198665)
Recommended Standards
- N-(4-Chloro-3-Nitrophenyl)-3-Fluorobenzamide (CAS 425647-14-9)
- 2-(4-Chloro-2-methoxyphenyl)-5,6-difluoro-1H-benzo[d]imidazole (CAS 1281980-66-2)
- N-(3-chloro-4-fluorophenyl)-3-nitrobenzamide (CAS 346723-73-7)
- (Isoquinolin-1-yl)zinc pivalate (0.58 mmol/g) (CAS 1643792-48-6)
- Eltrombopag impurity 152 (CAS 303066-62-8)
- Tofacitinib Impurity 144 (CAS 2091669-67-7)
- Abiraterone Impurity 42 (CAS CATO-C4X-107042)
- 6-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-methylnicotinonitrile (CAS 1355204-12-4)
- 2-(Difluoromethyl)-3-hydroxy-6-iodopyridine-4-acetonitrile (CAS 1807112-92-0)
- (S)-1-Tetralol (CAS 53732-47-1)
- 3-acetyl-2-hydroxybenzonitrile (CAS 128546-86-1)
- 5-(Naphthalen-2-yl)-1H-pyrrole-3-carbonitrile (CAS 1240949-41-0)
- Brivaracetam Impurity 11 (CAS CATO-C4X-200711)
- [Formaldehyde Schiff-base]-Semaglutide Impurity 136 X TFA Salt (CAS CATO-C4X-2226136)
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