Rifamycin Impurity 18 CAS CATO-C4X-200418
| CAS No. | CATO-C4X-200418 |
| Molecular Formula | C48H63N7O16S |
| Molecular Weight | 1026.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Rifamycin Impurity 18 (CAS CATO-C4X-200418) is a certified pharmaceutical impurity reference standard with the molecular formula C48H63N7O16S and a molecular weight of 1026.12 g/mol.
The molecular framework of Rifamycin Impurity 18 (C48H63N7O16S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C48H63N7O16S |
| Molecular Weight | 1026.12 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Rifamycin Standards
- Rifamycin Impurity 15 (CAS CATO-C4X-200414)
- Rifamycin Impurity 15 (CAS CATO-C4X-200415)
- Rifamycin Impurity 15 (CAS CATO-C4X-200411)
- Rifamycin Impurity 15 (CAS CATO-C4X-200412)
- Rifamycin Impurity 15 (CAS CATO-C4X-200413)
- Rifamycin impurity 19 (CAS 15271-73-5)
- Rifamycin Impurity 9 (CAS CATO-C4X-20049)
- Rifamycin Impurity 7 (CAS 59264-04-9)
Recommended Standards
- Tris[N,N,N,N-tetramethylguanidinium][tris(1S)-(1,1-binaphalene)-2,2-diolato]ytterbate (CAS 1611526-75-0)
- CAS CATO-C4X-34248 (CAS CATO-C4X-34248)
- Ru(ifpz)2(PPh2Me)2 , Bis(3-trifluoromethyl-5-(1-isoquinolyl)py (CAS 934276-37-6)
- PSS-(4-(Chloromethyl)phenyl)-Heptacyclopentyl substituted (CAS 307496-35-1)
- Cefotaxime Impurity 34 (CAS CATO-C4X-120134)
- Minocycline EP Impurity D (CAS 5679-00-5)
- Opicapone Impurity 91 (CAS CATO-C4X-240491)
- 4-(4-(Tert-butyl)phenyl)-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860612-54-0)
- 3-(2-Methyl-1H-indol-3-yl)-3-oxopropanenitrile (CAS 76397-72-3)
- 6-(Benzofuran-2-yl)-2-(pyridin-4-yl)-4H-chromen-4-one (CAS 652138-06-2)
- 1-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]piperazine dihydrochloride (CAS 1258650-98-4)
- 3-isoquinolinecarboxylic Acid, 1,2,3,4-tetrahydro-, Methyl Ester, (3r) (CAS 79799-05-6)
- Mycophenolate Mofetil Impurity 17 (CAS 26644-06-4)
- Pancreatic Polypeptide (31-36) Free Acid, human (CAS 192432-73-8)
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