Minocycline EP Impurity D CAS 5679-00-5
| CAS No. | 5679-00-5 |
| Molecular Formula | C21H23N3O7 |
| Molecular Weight | 429.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Minocycline EP Impurity D.
Minocycline EP Impurity D (CAS 5679-00-5) is a certified pharmaceutical impurity reference standard with the molecular formula C21H23N3O7 and a molecular weight of 429.42 g/mol.
The molecular framework of Minocycline EP Impurity D (C21H23N3O7) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Minocycline EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H23N3O7 |
| Molecular Weight | 429.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 3 |
Related Minocycline Standards
- Minocycline EP Impurity I (CAS 5874-95-3)
- Minocycline Impurity 68 (CAS CATO-C4X-169968)
- Minocycline Impurity 29 (CAS CATO-C4X-169929)
- Minocycline Impurity 69 (CAS CATO-C4X-169969)
- Minocycline Impurity 61 (CAS CATO-C4X-169961)
- Minocycline impurity 55 (CAS CATO-C4X-169955)
- Minocycline Impurity 58 (CAS CATO-C4X-169958)
- Minocycline Impurity 60 (CAS CATO-C4X-169960)
Recommended Standards
- 4-Dimethyl Minocycline (CAS 885112-29-8)
- Amicycline hydrochloride, >88% (HPLC) (CAS 4199-34-2)
- Boc-Trp(For)-OSu (CAS 70601-13-7)
- 2-(4-Methoxyphenyl)-5-phenyl-1,3,4-oxadiazole (CAS 842-79-5)
- Lisinopril EP Impurity I (CAS CATO-C4X-16819)
- Afoxolaner Impurity 14 (CAS 1125726-30-8)
- Clofarabine Impurity 5 (CAS CATO-C4X-15935)
- 642-31-9 9-Anthraldehyde Anthracene-9-carbaldehyde 9-Anthracenecarboxaldehyde 9-Anthraldehyde (8CI) 9-Anthrylaldehyde 9-Anthrylcarboxaldehyde CCRIS 3165 EINECS 211-383-0 9-Formylanthracene NSC 15 EC 211-383-0 (CAS 642-31-9)
- (2S,3R)-1-benzyl-3-fluoro-2-(trifluoromethyl)piperidine (CAS 1782959-05-0)
- Amlodipine EP Impurity G (CAS 43067-01-2)
- Methyl 4-(5,5-dimethyl-1,3-dioxan-2-yl)benzoate (CAS 138536-73-9)
- n-(4-Chlorobenzyl)-1-cyclopropylmethanamine (CAS 1019506-76-3)
- 4-Bromo-3-(methoxymethyl)benzoic acid (CAS 1141473-98-4)
- a-Bag Cell Peptide (1-8) (CAS 87549-53-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com