Lornoxicam Impurity 18 CAS CATO-C4X-201618
| CAS No. | CATO-C4X-201618 |
| Molecular Formula | C5H4ClNO4S |
| Molecular Weight | 209.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Lornoxicam Impurity 18 (C5H4ClNO4S) is characterized by a carbohydrate-derived structure, an amide group, a sulfone group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Lornoxicam Impurity 18 (CAS CATO-C4X-201618, C5H4ClNO4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H4ClNO4S |
| Molecular Weight | 209.61 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Lornoxicam Standards
- Lornoxicam Impurity 16 (CAS 72975-44-1)
- Lornoxicam Impurity 42 (CAS CATO-C4X-201642)
- Lornoxicam impurity 94 (CAS CATO-C4X-201694)
- Lornoxicam Impurity 1 (CAS 187746-97-0)
- Lornoxicam Impurity 26 (CAS 59804-27-2)
- Lornoxicam Impurity 41 (CAS CATO-C4X-201641)
- Lornoxicam Impurity 34 (CAS 1333316-61-2)
- Lornoxicam Impurity 20 (CAS 54166-60-8)
Recommended Standards
- 2-Chloro-4-(2-fluoropyridin-4-yl)pyrimidine, 97% (CAS 361147-25-3)
- 3-Amino-1-(4-chlorophenyl)-4,5-dihydro-1h-pyrazol-5-one (CAS 10050-12-1)
- 2-Chloro-4-(2-fluoropyridin-3-yl)pyrimidine (CAS 954216-54-7)
- 5-(Chloromethyl)-3-(3-methylpyridin-2-yl)-1,2,4-oxadiazole (CAS 1009562-65-5)
- Sivelestat Impurity 28 (CAS CATO-C4X-212328)
- Topicamide lmpurity 9 (CAS CATO-C4X-21509)
- Clopidogrel Impurity 45 (Mixture of Diastereomers) (CAS CATO-C4X-102945)
- 2,4-Dichloro-6-methoxy-1,5-naphthyridine (CAS 959990-35-3)
- Lactose Octaacetate (CAS 23973-20-8)
- 6-chloro-3-hydroxyquinoline-4-carboxylic acid (CAS 856177-13-4)
- D-Har Eptifibatide Trifluoroacetic acid (CAS CATO-C4X-23452)
- 3-(Piperidin-4-yl)-1,3-oxazinan-2-one hydrochloride (CAS 1233955-65-1)
- 2,2,6,6-tetradeuteriomorpholine (CAS 35530-94-0)
- Palmitoyl Pentapeptide-4 (CAS 214047-00-4)
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