Lornoxicam impurity 49 CAS CATO-C4X-201649
| CAS No. | CATO-C4X-201649 |
| Molecular Formula | C9H11ClO5S2 |
| Molecular Weight | 298.76 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lornoxicam impurity 49.
As a process- or degradation-related impurity, Lornoxicam impurity 49 (CAS CATO-C4X-201649, C9H11ClO5S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lornoxicam impurity 49 (C9H11ClO5S2) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H11ClO5S2 |
| Molecular Weight | 298.76 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 2 |
Related Lornoxicam Standards
- Lornoxicam impurity 67 (CAS CATO-C4X-201667)
- Lornoxicam impurity 58 (CAS CATO-C4X-201658)
- Lornoxicam Impurity 13 (CAS 2322849-92-1)
- Lornoxicam impurity 52 (CAS 906522-88-1)
- Lornoxicam Impurity 28 (CAS CATO-C4X-201628)
- Lornoxicam Impurity 37 (CAS 106820-63-7)
- Lornoxicam Impurity 109 (CAS CATO-C4X-2016109)
- Lornoxicam Impurity 79 (CAS 1629463-16-6)
Recommended Standards
- Baclofen impurity 9 (CAS 101104-10-3)
- 951889-86-4 8-(5-Chloro-2-methoxyphenyl)-8-oxooctanoic acid MFCD09801756 (CAS 951889-86-4)
- 2-Chloro-n-{[(2-methoxyphenyl)carbamoyl]methyl}-n-propylacetamide (CAS 1049604-75-2)
- Ethyl 6-(5-chloro-2-methoxyphenyl)-6-oxohexanoate (CAS 951886-73-0)
- Amantadine EP Impurity A (CAS 935-56-8)
- Risdiplam Impurity 3 (CAS CATO-C4X-30123)
- Piracetam Impurity 13 (CAS 105-39-5)
- 1,3-Diphenyl-4-(2-(p-tolyl)hydrazono)-1H-pyrazol-5(4H)-one (CAS 6528-22-9)
- 2-(4-Methylpiperazin-1-yl)cyclopentan-1-amine (CAS 953895-57-3)
- Corticosterone (CAS 50-22-6)
- 4-(4-Bromophenyl)-6-methylpyrimidin-2-amine (CAS 792942-45-1)
- 4-(prop-2-yn-1-yl)piperazin-1-amine (CAS 56964-23-9)
- Tert-butyl 4-((3-(methoxycarbonyl)phenyl)sulfonamido)piperidine-1-carboxylate (CAS 1286264-41-2)
- [3,5 Diiodo-Tyr7] Peptide T (CAS 128551-40-6)
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