Crisaborole lmpurity 70 CAS CATO-C4X-202170
| CAS No. | CATO-C4X-202170 |
| Molecular Formula | C15H12BNO3 |
| Molecular Weight | 265.07 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Crisaborole lmpurity 70 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Crisaborole lmpurity 70 (CAS CATO-C4X-202170) is a certified pharmaceutical impurity reference standard with the molecular formula C15H12BNO3 and a molecular weight of 265.07 g/mol.
The molecular framework of Crisaborole lmpurity 70 (C15H12BNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Crisaborole lmpurity 70 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H12BNO3 |
| Molecular Weight | 265.07 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Crisaborole Standards
- Crisaborole Impurity 40 (CAS 13321-75-0)
- Crisaborole Impurity 39 (CAS 13321-76-1)
- Crisaborole Impurity 66 (CAS 2247957-30-6)
- Crisaborole Impurity 54 (CAS 2990481-66-6)
- Crisaborole Impurity 140 (CAS CATO-C4X-2021140)
- Crisaborole Impurity 17 (CAS 1187188-59-5)
- Crisaborole Impurity 49 (CAS CATO-C4X-202149)
- Crisaborole Impurity 16 (CAS 906673-43-6)
Recommended Standards
- 951889-30-8 2-Bromo-3-[(2-trifluoromethyl)phenyl]-1-propene MFCD09801105 (CAS 951889-30-8)
- 3-(4-Bromo-3-fluorophenoxy)propane-1,2-diol (CAS 1548539-95-2)
- 9-Bromo-[1,2,4]triazolo[1,5-c]quinazolin-5(6H)-one (CAS 882517-92-2)
- Ethyl 4-bromo-1-(2-fluoroethyl)-1H-pyrazole-5-carboxylate (CAS 1856062-70-8)
- Rosuvastatin Impurity 144 (CAS CATO-C4X-1169144)
- Cinitapride Impurity 23 (CAS 1114847-86-7)
- Finerenone Impurity 263 (CAS CATO-C4X-2880263)
- 6-Amino-5-(difluoromethyl)-4-hydroxypicolinic acid (CAS 1805953-38-1)
- (1S)-1-(5-Fluoropyridin-2-yl)ethan-1-ol (CAS 1016227-97-6)
- 5-Chloro-2-(2-(trifluoromethoxy)phenoxy)aniline (CAS 1777120-70-3)
- Sodium metatitanate (CAS 12034-36-5)
- n1-Cyclopropyl-n3-ethyl-n3-isobutylpropane-1,3-diamine (CAS 1184165-38-5)
- Dihexyl malonate (CAS 1431-37-4)
- Semaglutide Impurity 13 (CAS CATO-C4X-222613)
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